Epidermal appendage tumor

Summary

Epidermal appendage tumor (MONDO:0002297) is a cancer (an umbrella term covering 5 Mondo subtypes) and 1 clinical trial. A subtype of skin neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Umbrella term: 5 Mondo subtypes
• Clinical trials: 1

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	epidermal appendage tumor
Mondo ID	MONDO:0002297
DOID	DOID:2433
NCIT	C4463
SNOMED CT	126489007
UMLS	C0345988
MedGen	87527
Anatomy (UBERON)	UBERON:0000021
Is cancer (heuristic)	yes

Also known as: adnexal neoplasm of skin · adnexal neoplasm of the skin · adnexal tumor of skin · adnexal tumor of the skin · adnexal tumour of skin · adnexal tumour of the skin · cutaneous adnexal neoplasm · cutaneous appendage neoplasm · cutaneous appendage neoplasm (disease) · cutaneous appendage tumor · cutaneous appendage tumour · Epidermal appendage neoplasm · Epidermal appendage tumour · neoplasm of cutaneous appendage · neoplasm of Epidermal appendage · neoplasm of skin appendage · skin appendage neoplasm · skin appendage tumor · tumor of cutaneous appendage · tumor of Epidermal appendage (+6 more)

Disease family

This is a subtype of skin neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › skin neoplasm › epidermal appendage tumor

Related subtypes (16): dermoid cyst of skin, eyelid neoplasm, dermis tumor, skin cancer, benign dermal neurilemmoma, actinic keratosis, familial Dupuytren contracture, schwannomatosis, familial multiple discoid fibromas, Maffucci syndrome, hemangiopericytoma of skin, benign neoplasm of skin, melanocytic skin neoplasm, epithelial skin neoplasm, calcifying epithelial odontogenic tumor, familial hyperphosphatemic tumoral calcinosis/hyperphosphatemic hyperostosis syndrome

Subtypes (5): sweat gland neoplasm, hair follicle neoplasm, sebaceous gland neoplasm, skin appendage carcinoma, hamartoma of skin appendage

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 1.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT03210935	Not specified	RECRUITING	French National Database of Rare Dermatological Cancers