Epidural spinal canal neoplasm

Summary

Epidural spinal canal neoplasm (MONDO:0002713) is a cancer and 1 clinical trial. Top therapeutic interventions include pembrolizumab. A subtype of vertebral column disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Clinical trials: 1

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	epidural spinal canal neoplasm
Mondo ID	MONDO:0002713
MeSH	D015174
DOID	DOID:3618
NCIT	C3019
UMLS	C0014536
MedGen	4504
Anatomy (UBERON)	UBERON:0003691
Is cancer (heuristic)	yes

Also known as: epidural neoplasm · epidural space neoplasm · epidural space tumor · epidural space tumour · epidural spinal canal tumor · epidural spinal canal tumors · epidural spinal canal tumour · epidural spinal canal tumours · epidural spinal neoplasms · epidural spinal tumors · epidural spinal tumours · epidural tumor · epidural tumour · extradural neoplasm · extradural spinal canal neoplasm · extradural spinal canal neoplasms · extradural spinal canal tumor · extradural spinal canal tumour · extradural spinal neoplasms · extradural spinal tumors (+17 more)

Disease family

This is a subtype of vertebral column disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › musculoskeletal system disorder › skeletal system disorder › vertebral column disorder › epidural spinal canal neoplasm

Related subtypes (14): spondylocostal dysostosis, sacrum chordoma, Baastrup syndrome, lumbosacral lipoma, spinal stenosis, intervertebral disk degenerative disorder, coccygodynia, vertebral joint disorder, sacrococcygeal teratoma, spinal cord injury, tuberculosis, spinal, vertebral disorder, lumbar disk disease, dropped head syndrome

Subtypes (2): epidural spinal canal angiolipoma, intradural extramedullary spinal canal neoplasm

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 1.

Phase distribution (across all retrieved trials)

Phase	Trials
EARLY_PHASE1	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT05204290	EARLY_PHASE1	TERMINATED	Study of Combined Decompressive Spine Radiosurgery and Pembrolizumab

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
PEMBROLIZUMAB	4	1