Esophageal neuroendocrine tumor

Summary

Esophageal neuroendocrine tumor (MONDO:0003649) is a cancer. A subtype of digestive system neuroendocrine tumor, grade 1/2 — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	esophageal neuroendocrine tumor
Mondo ID	MONDO:0003649
Orphanet	506136
DOID	DOID:5784
ICD-11	1167478749, 890879256
NCIT	C95616
UMLS	C2987260
MedGen	459486
GARD	0022058
Anatomy (UBERON)	UBERON:0001043
Is cancer (heuristic)	yes

Also known as: esophageal NEN · esophageal NET · esophageal neuroendocrine neoplasm · esophageal neuroendocrine tumor · esophageal well differentiated endocrine tumor · esophageal well differentiated endocrine tumor/carcinoma · esophageal well differentiated endocrine tumour · esophagus NET · esophagus neuroendocrine neoplasm · esophagus neuroendocrine tumor · esophagus neuroendocrine tumor, well differentiated, low or intermediate grade · NEN of esophagus · NEN of oesophagus · neuroendocrine neoplasm of esophagus · neuroendocrine neoplasm of oesophagus · neuroendocrine tumour of oesophagus · oesophagus NET · oesophagus neuroendocrine neoplasm · oesophagus neuroendocrine tumor, well differentiated, low or intermediate grade · oesophagus neuroendocrine tumour

Data availability: 5 cell lines.

Disease family

This is a subtype of digestive system neuroendocrine tumor, grade 1/2. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › digestive system disorder › digestive system neuroendocrine neoplasm › digestive system neuroendocrine tumor, grade 1/2 › esophageal neuroendocrine tumor

Related subtypes (9): small intestine neuroendocrine tumor, well differentiated, low or intermediate grade, gastrin-producing neuroendocrine tumor, L-cell glucagon-like peptide-producing neuroendocrine tumor, gastric neuroendocrine tumor, well differentiated, low or intermediate grade, neuroendocrine tumor of the colon, well differentiated, low or intermediate grade tumor, rectal neuroendocrine tumor, gallbladder neuroendocrine tumor, grade 1/2, pancreatic neuroendocrine tumor, intestinal neuroendocrine tumor G1

Subtypes (1): esophageal small cell neuroendocrine carcinoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.