Eye allergy

disease
On this page

Summary

Eye allergy (MONDO:0005551) is a disease and 2 clinical trials. Top therapeutic interventions include olopatadine. A subtype of allergic disease — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

  • Clinical trials: 2

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

FieldValue
Canonical nameeye allergy
Mondo IDMONDO:0005551
EFOEFO:0005751
UMLSC0852875
MedGen1843485
Anatomy (UBERON)UBERON:0000019
Is cancer (heuristic)no

Disease family

This is a subtype of allergic disease. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › immune system disorderhypersensitivity reaction diseaseallergic diseaseeye allergy

Related subtypes (11): allergic respiratory disease, drug allergy, gastrointestinal allergy, latex allergy, atopic eczema, atopic IgE-mediated allergic disorder, vulvovaginitis, allergic seminal, allergic otitis media, alpha-gal syndrome, venom allergy, food allergy

Subtypes (2): allergic contact dermatitis of eyelid, atopic conjunctivitis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

Drugs indicated for this disease

18 approved. Disease-direct ChEMBL indications, not inferred from the associated-gene cohort below.

DrugDevelopment status
AlcaftadineApproved (phase 4)
AzelastineApproved (phase 4)
BilastineApproved (phase 4)
BrimonidineApproved (phase 4)
CetirizineApproved (phase 4)
CromolynApproved (phase 4)
EmedastineApproved (phase 4)
EpinastineApproved (phase 4)
KetotifenApproved (phase 4)
LevocabastineApproved (phase 4)
LodoxamideApproved (phase 4)
NaphazolineApproved (phase 4)
NedocromilApproved (phase 4)
OlopatadineApproved (phase 4)
OxymetazolineApproved (phase 4)
PhenylephrineApproved (phase 4)
TetrahydrozolineApproved (phase 4)
XylometazolineApproved (phase 4)

Clinical trials & evidence

Clinical trials

Clinical trials: 2.

Phase distribution (across all retrieved trials)

PhaseTrials
Not specified2

Top trials by phase / activity

NCTPhaseStatusTitle
NCT07404956Not specifiedRECRUITINGTHE EFFECT OF SURGICAL MASK AND N95 MASK USE ON SURGICAL SMOKE IN OPERATING ROOM NURSES
NCT01450176Not specifiedCOMPLETEDComparing Patient Satisfaction With Pataday or Bepreve

Drugs tested across these trials (top 30)

MoleculeMax phaseTrials referencing
OLOPATADINE41