Eyelid neoplasm

Summary

Eyelid neoplasm (MONDO:0002235) is a cancer and 6 clinical trials. Top therapeutic interventions include sonidegib. A subtype of skin neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Clinical trials: 6

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	eyelid neoplasm
Mondo ID	MONDO:0002235
EFO	EFO:1000934
MeSH	D005142
Orphanet	98580
DOID	DOID:2173
NCIT	C3031
SNOMED CT	278697001
UMLS	C0015424
MedGen	41939
Anatomy (UBERON)	UBERON:0001711
Is cancer (heuristic)	yes

Also known as: eyelid neoplasm · eyelid neoplasm (disease) · eyelid tumor · eyelid tumour · neoplasm of eyelid · neoplasm of the eyelid · palpebral tumor · palpebral tumour · tumor of eyelid · tumor of the eyelid · tumour of eyelid · tumour of the eyelid

Disease family

This is a subtype of skin neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › skin neoplasm › eyelid neoplasm

Related subtypes (16): dermoid cyst of skin, epidermal appendage tumor, dermis tumor, skin cancer, benign dermal neurilemmoma, actinic keratosis, familial Dupuytren contracture, schwannomatosis, familial multiple discoid fibromas, Maffucci syndrome, hemangiopericytoma of skin, benign neoplasm of skin, melanocytic skin neoplasm, epithelial skin neoplasm, calcifying epithelial odontogenic tumor, familial hyperphosphatemic tumoral calcinosis/hyperphosphatemic hyperostosis syndrome

Subtypes (3): palpebral epidermal tumor, neurogenic palpebral tumor, benign eyelid neoplasm

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 6.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	5
PHASE4	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT05294640	PHASE4	COMPLETED	Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures
NCT04235803	Not specified	UNKNOWN	Telemedicine Follow-up for Routine, Low-Risk Oculoplastic Surgery
NCT05072327	Not specified	UNKNOWN	Mohs Surgery Combind With Cryotherapy for Eyelid Malignant Tumors.
NCT06206681	Not specified	UNKNOWN	Efficacy and Safety of Ultrapulse Carbon Dioxide Laser Treatment in Eyelid Tumors
NCT06279143	Not specified	COMPLETED	The Diagnostic Accuracy of Advanced Imaging in Identifying Suspected Skin Cancer (Basal Cell Carcinoma) Around the Eyes
NCT07068568	Not specified	COMPLETED	Dose-Modulated Sonidegib Therapy for Periocular Basal Cell Carcinoma

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
SONIDEGIB	4	1