Fetal parvovirus syndrome
disease diseaseOn this page
Also known as fifth diseaseHuman parvovirus B19 caused infectious embryofetopathyHuman parvovirus B19 infectious embryofetopathyMaternofetal infection by parvovirusmother-to-child transmission of parvovirus syndromeParvovirus antenatal infectionParvovirus B19 antenatal infection
Summary
Fetal parvovirus syndrome (MONDO:0017453) is a disease. A subtype of infectious embryofetopathy — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Prevalence: Unknown (Worldwide)
- Phenotypes (HPO): 9
Clinical features
Signs & symptoms
Clinical features (HPO)
9 HPO clinical features (Orphanet curated; top 9 by frequency):
| HPO ID | Term | Frequency |
|---|---|---|
| HP:0001541 | Ascites | Very frequent (80-99%) |
| HP:0001789 | Hydrops fetalis | Very frequent (80-99%) |
| HP:0001873 | Thrombocytopenia | Very frequent (80-99%) |
| HP:0001903 | Anemia | Very frequent (80-99%) |
| HP:0000478 | Abnormality of the eye | Occasional (5-29%) |
| HP:0000504 | Abnormality of vision | Occasional (5-29%) |
| HP:0001511 | Intrauterine growth retardation | Occasional (5-29%) |
| HP:0001639 | Hypertrophic cardiomyopathy | Occasional (5-29%) |
| HP:0010880 | Increased nuchal translucency | Occasional (5-29%) |
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | fetal parvovirus syndrome |
| Mondo ID | MONDO:0017453 |
| MeSH | C536301 |
| Orphanet | 295 |
| ICD-11 | 648536096 |
| SNOMED CT | 715197005 |
| UMLS | C2931167 |
| MedGen | 443992 |
| GARD | 0004236 |
| Is cancer (heuristic) | no |
Also known as: fifth disease · Human parvovirus B19 caused infectious embryofetopathy · Human parvovirus B19 infectious embryofetopathy · Maternofetal infection by parvovirus · mother-to-child transmission of parvovirus syndrome · Parvovirus antenatal infection · Parvovirus B19 antenatal infection
Disease family
Classification path: disease › human disease › disease by etiologic mechanism › disease of primarily extrinsic mechanism › infectious disease › infectious embryofetopathy › fetal parvovirus syndrome
Related subtypes (9): congenital syphilis, congenital toxoplasmosis, congenital rubella syndrome, congenital varicella syndrome, congenital enterovirus infection, congenital Epstein-Barr virus infection, fetal enterovirus syndrome, fetal parainfluenza virus type 3 syndrome, congenital herpes virus infection
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 0.
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.