Foodborne botulism

disease
On this page

Also known as intoxication botulism

Summary

Foodborne botulism (MONDO:0016453) is a disease. A subtype of botulism — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

  • Prevalence: Unknown (Worldwide) [Orphanet-validated]
  • Phenotypes (HPO): 19

Clinical features

Epidemiology

Prevalence records

3 prevalence record(s), Orphanet:

TypeClassValueGeographyValidation
Annual incidence1-9 / 1 000 0000.1EuropeValidated
Annual incidence<1 / 1 000 0000.01United StatesValidated
Annual incidence1-9 / 1 000 0000.18RomaniaValidated

Signs & symptoms

Clinical features (HPO)

19 HPO clinical features (Orphanet curated; top 19 by frequency):

HPO IDTermFrequency
HP:0000217XerostomiaVery frequent (80-99%)
HP:0000508PtosisVery frequent (80-99%)
HP:0000651DiplopiaVery frequent (80-99%)
HP:0001260DysarthriaVery frequent (80-99%)
HP:0001324Muscle weaknessVery frequent (80-99%)
HP:0002014DiarrheaVery frequent (80-99%)
HP:0002015DysphagiaVery frequent (80-99%)
HP:0002019ConstipationVery frequent (80-99%)
HP:0002027Abdominal painVery frequent (80-99%)
HP:0003470ParalysisVery frequent (80-99%)
HP:0006597Diaphragmatic paralysisVery frequent (80-99%)
HP:0006824Cranial nerve paralysisVery frequent (80-99%)
HP:0011499MydriasisVery frequent (80-99%)
HP:0100021Cerebral palsyVery frequent (80-99%)
HP:0000016Urinary retentionFrequent (30-79%)
HP:0002017Nausea and vomitingFrequent (30-79%)
HP:0002747Respiratory insufficiency due to muscle weaknessFrequent (30-79%)
HP:0011675ArrhythmiaFrequent (30-79%)
HP:0006543Cardiorespiratory arrestOccasional (5-29%)

Identifiers

Disease identifiers

FieldValue
Canonical namefoodborne botulism
Mondo IDMONDO:0016453
Orphanet228371
DOIDDOID:0050352
ICD-112033726602
NCITC128341
SNOMED CT398523009
UMLSC1739094
MedGen320728
GARD0020591
Is cancer (heuristic)no

Also known as: intoxication botulism

Disease family

This is a subtype of botulism. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › disease of primarily extrinsic mechanism › infectious diseasebacterial infectious diseaseprimary bacterial infectious diseasebotulismfoodborne botulism

Related subtypes (3): toxin-mediated infectious botulism, inhalational botulism, iatrogenic botulism

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.

No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.