Fourth cranial nerve palsy

Summary

Fourth cranial nerve palsy (MONDO:0001146) is a disease and 2 clinical trials. A subtype of cranial nerve palsy — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 2

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	fourth cranial nerve palsy
Mondo ID	MONDO:0001146
DOID	DOID:10869
ICD-11	120848300
SNOMED CT	20610004
UMLS	C0271375
MedGen	75746
Anatomy (UBERON)	UBERON:0001644
Is cancer (heuristic)	no

Also known as: cranial nerve palsy of trochlear nerve · fourth nerve palsy · fourth or trochlear nerve palsy · trochlear nerve cranial nerve palsy

Disease family

This is a subtype of cranial nerve palsy. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › nervous system disorder › cranial nerve neuropathy › cranial nerve palsy › fourth cranial nerve palsy

Related subtypes (6): oculomotor nerve paralysis, multiple cranial nerve palsy, glossopharyngeal nerve paralysis, Bell’s palsy, abducens nerve palsy, progressive bulbar palsy

Subtypes (1): congenital trochlear nerve palsy

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 2.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	2

Top trials by phase / activity

NCT	Phase	Status	Title
NCT03059420	Not specified	RECRUITING	Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies
NCT02149355	Not specified	UNKNOWN	Teeth and Jaw Misalignment in Patients Suffering From Congenital Fourth Cranial Nerve Palsy