Functioning pituitary gland adenoma

Summary

Functioning pituitary gland adenoma (MONDO:0003429) is a cancer (an umbrella term covering 5 Mondo subtypes). A subtype of functioning pituitary gland neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Umbrella term: 5 Mondo subtypes

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	functioning pituitary gland adenoma
Mondo ID	MONDO:0003429
Orphanet	314753
DOID	DOID:5395
NCIT	C8388
UMLS	C0854486
MedGen	163135
GARD	0021389
Anatomy (UBERON)	UBERON:0000007
Is cancer (heuristic)	yes

Also known as: endocrine active pituitary adenoma · functioning adenoma of pituitary · functioning adenoma of pituitary gland · functioning adenoma of the pituitary · functioning adenoma of the pituitary gland · functioning pituitary adenoma · functioning pituitary gland adenoma · functioning pituitary gland adenoma (benign) · secreting pituitary adenoma · secretory adenoma of pituitary · secretory adenoma of pituitary gland · secretory adenoma of the pituitary · secretory adenoma of the pituitary gland · secretory pituitary adenoma · secretory pituitary gland adenoma

Disease family

This is a subtype of functioning pituitary gland neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › endocrine gland neoplasm › pituitary tumor › functioning pituitary gland neoplasm › functioning pituitary gland adenoma

Subtypes (5): TSH producing pituitary tumor, Cushing disease due to pituitary adenoma, Nelson syndrome, mixed functioning pituitary adenoma, functioning gonadotropic adenoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.