Hantavirus hemorrhagic fever with renal syndrome
diseaseOn this page
Also known as hemorrhagic fever, Russianhemorrhagic nephrosonephritisHFRSPuumala virus nephropathy
Summary
Hantavirus hemorrhagic fever with renal syndrome (MONDO:0005784) is a disease and 3 clinical trials. A subtype of renal infectious disease — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 3
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | hantavirus hemorrhagic fever with renal syndrome |
| Mondo ID | MONDO:0005784 |
| DOID | DOID:11266 |
| ICD-10-CM | A98.5 |
| NCIT | C84753 |
| SNOMED CT | 102455002 |
| GARD | 0027728 |
| Anatomy (UBERON) | UBERON:0002113 |
| Is cancer (heuristic) | no |
Also known as: hemorrhagic fever, Russian · hemorrhagic nephrosonephritis · HFRS · Puumala virus nephropathy
Disease family
This is a subtype of renal infectious disease. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › urinary system disorder › kidney disorder › renal infectious disease › hantavirus hemorrhagic fever with renal syndrome
Related subtypes (3): renal tuberculosis, pyelonephritis, adenovirus renal infection
Subtypes (4): Hantavirus hemorrhagic fever with renal syndrome, Seoul virus type, Hantavirus hemorrhagic fever with renal syndrome, Puumala virus type, Hantavirus hemorrhagic fever with renal syndrome, Dobrava-Belgrade virus type, BK-virus nephropathy
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 3.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| PHASE4 | 1 |
| PHASE2 | 1 |
| Not specified | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT06009042 | PHASE4 | UNKNOWN | Efficacy of Intravenous Immunoglobulin in Patients With Hemorrhagic Fever With Renal Syndrome: a Prospective Study |
| NCT04333459 | PHASE2 | COMPLETED | Safety/Immunogenicity Hantaan Virus DNA Vaccine and Puumala Virus DNA Vaccine, For Prevention of HFRS |
| NCT06020326 | Not specified | UNKNOWN | A Retrospective Cohort Study of HFRS |
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.