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Atlas / Disease / Hearing disorder

Hearing disorder

disease
On this page

Summary

Hearing disorder (MONDO:0021945) is a disease and 45 clinical trials. Top therapeutic interventions include sodium chloride and ancrod. A subtype of auditory system disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

  • Clinical trials: 45

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

FieldValue
Canonical namehearing disorder
Mondo IDMONDO:0021945
MeSHD006311
NCITC3078
SNOMED CT128540005
UMLSC0260662
MedGen82636
Is cancer (heuristic)no

Also known as: hearing disorder

Disease family

This is a subtype of auditory system disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › auditory system disorder › hearing disorder

Related subtypes (10): discharging ear, dislocation of ear ossicle, adhesive otitis media, retrocochlear disease, inner ear disorder, external ear disorder, middle ear disorder, auditory system cancer, inherited auditory system disease, auditory system benign neoplasm

Subtypes (4): cortical deafness, hearing loss disorder, hyperacusis, tinnitus

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 45.

Phase distribution (across all retrieved trials)

PhaseTrials
Not specified41
PHASE1/PHASE23
PHASE2/PHASE31

Top trials by phase / activity

NCTPhaseStatusTitle
NCT00486577PHASE2/PHASE3COMPLETEDChronic Electrical Stimulation of the Auditory Cortex for Intractable Tinnitus
NCT06370351PHASE1/PHASE2RECRUITINGA Phase I/II Clinical Trial with SENS-501 in Children Suffering from Severe to Profound Hearing Loss Due to Otoferlin (OTOF) Mutations
NCT07304024PHASE1/PHASE2RECRUITINGA Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound
NCT01621256PHASE1/PHASE2COMPLETEDEfficacy, Safety, and Tolerability of Ancrod in Patients With Sudden Hearing Loss
NCT00341874Not specifiedENROLLING_BY_INVITATIONGenetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan
NCT03429036Not specifiedRECRUITINGBiospecimen Procurement for Head and Neck Disorders
NCT04934371Not specifiedNOT_YET_RECRUITINGTreatment of Tinnitus With Noninvasive Neuromodulation and Listening Therapy
NCT05859568Not specifiedENROLLING_BY_INVITATIONBaseline Performance and Fitting Parameters for Sonova Products
NCT05936034Not specifiedRECRUITINGComparative Study of the Quality of Life of Patients Suffering From OTOTOXICITY Due to Chemotherapy Based on Platinum Salts Fitted With a Hearing Aid Compared to Those Not Fitted.
NCT05973669Not specifiedENROLLING_BY_INVITATIONMED-EL Remote Care Multi-Center Feasibility Study
NCT06051968Not specifiedACTIVE_NOT_RECRUITINGEffects of an Online Hearing Support for First-time Hearing Aid Users
NCT06164483Not specifiedRECRUITINGAuditory Functions in Patients With Multiple Sclerosis
NCT06303180Not specifiedRECRUITINGNIDCD Otolaryngology Clinical Protocol Biospecimen Bank
NCT06468137Not specifiedENROLLING_BY_INVITATIONFollow Up of an Online Hearing Support for First-time Hearing Aid Users
NCT06882434Not specifiedNOT_YET_RECRUITINGHolistic Integration for Healthy Longevity and Aging in Place
NCT07081542Not specifiedNOT_YET_RECRUITINGComparative Analysis of Hearing Outcomes: Robotic vs. Manual Insertion of Cochlear Implants
NCT07089485Not specifiedNOT_YET_RECRUITINGImpact of Anesthesia Alarm Volume on Mental Workload in Surgical Trainees
NCT07402941Not specifiedRECRUITINGEvaluation of Cochlear (Promontory) Stimulation During Awake Ear Surgery (TONES Study)
NCT00023049Not specifiedCOMPLETEDGenetic Analysis of Hereditary Disorders of Hearing and Balance
NCT00359931Not specifiedCOMPLETEDBrain Imaging of Tinnitus
NCT01212068Not specifiedTERMINATEDConnectivity Analysis for Investigation of Auditory Impairment in Epilepsy
NCT01738490Not specifiedCOMPLETEDLong-term Stability and Survival Rates of a Novel Oticon Medical Bone Conduction Device Implant
NCT01959152Not specifiedTERMINATEDEvaluation of Hearing Preservation in Adults With Partial Low-Frequency Hearing Implanted With the HiFocus™ Mid-Scala Electrode
NCT01977521Not specifiedUNKNOWNTranscranial Direct Current Stimulation as Treatment for Auditory Hallucinations
NCT02189798Not specifiedTERMINATEDImplantation of the HiRes90K™ Advantage Cochlear Implant With HiFocus™ Mid-Scala and Development of a Combined Electric and Acoustic Stimulation Technology in Adults With Partial Deafness
NCT02453633Not specifiedUNKNOWNTheory Based SMS Reminders - Text’s Impact on Patient Attendance
NCT02684175Not specifiedCOMPLETEDComparison of In-Person Versus Remote Cochlear Implant Candidacy Evaluations
NCT02811549Not specifiedCOMPLETEDBenefits of the HiResolution Bionic Ear System in Adults With Asymmetric Hearing Loss
NCT03225157Not specifiedCOMPLETEDHearing Loss and the Effects of Statin Drugs in People With Head and Neck Squamous Cell Carcinoma Treated With Cisplatin Chemoradiation
NCT03429777Not specifiedWITHDRAWNValidation of a Smartphone-Based Hearing-in-Noise Test (HearMe)
NCT03512951Not specifiedCOMPLETEDSubjective Evaluation of a Sound Processing Method for Hearing Aids on Auditory Distance Perception
NCT03666910Not specifiedUNKNOWNHearing Problems in Children of Rheumatic Diseased Mothers
NCT03847753Not specifiedCOMPLETEDExploring the Comorbidity Between Mental Disorders and General Medical Conditions
NCT04237207Not specifiedCOMPLETEDClinical Evaluation of a Cochlear Implant Sound Processor
NCT04875637Not specifiedUNKNOWNMiddle-ear Reflex Testing Using Wideband Acoustic Immittance
NCT05034731Not specifiedCOMPLETEDEvaluation of Remote Fitting in Adult and Pediatric Users of the HiResolution Bionic Ear System
NCT05086809Not specifiedCOMPLETEDInvestigation of an Updated Bone-anchored Sound Processor
NCT05117801Not specifiedUNKNOWNEvaluation of Pétale® (Small Hearing Test Equipment for Children) for the Screening of Hearing Disorders in Children From 9 Months to 3 Years Old by the General Practitioner or Pediatrician
NCT05189587Not specifiedUNKNOWNHome-based Transcranial Electrical Stimulation (TES) in Patients With Chronic Tinnitus
NCT05222230Not specifiedUNKNOWNFFP3 Respirators and Ears - Effects on Middle Ear Pressure and Hearing

Drugs tested across these trials (top 30)

MoleculeMax phaseTrials referencing
SODIUM CHLORIDE41
ANCROD31

About this page

Generated deterministically by Sugi Atlas from primary biomedical databases via BioBTree. Every record on this page traces to a primary source.

Generated
Atlas version
v1.1.2
BioBTree
v2.0.2

Sources 19

This page pulls from 19 datasets indexed by BioBTree:

chembl_moleculecivic_evidenceclinical_trialsclinvarefogenccgwasgwas_studyhgncmedgenmeshmimmondomondochildmondoparentncitorphanetsctidumls