Heart neoplasm

Summary

Heart neoplasm (MONDO:0021209) is a cancer (an umbrella term covering 10 Mondo subtypes) and 8 clinical trials. A subtype of heart disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Umbrella term: 10 Mondo subtypes
• Clinical trials: 8

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	heart neoplasm
Mondo ID	MONDO:0021209
EFO	EFO:1001339
NCIT	C3081
UMLS	C0018809
MedGen	9172
GARD	0002619
Anatomy (UBERON)	UBERON:0000948
Is cancer (heuristic)	yes

Also known as: Cardiac neoplasm · Cardiac neoplasms · Cardiac tumor · Cardiac tumour · heart neoplasm (disease) · heart tumor · heart tumour · Intracavitary tumors · Intracavitary tumours · myocardial tumors (rhabdomyomas and fibromas) · myocardial tumours (rhabdomyomas and fibromas) · neoplasm of heart · neoplasm of the heart · primary cardiac tumors, childhood · tumor of heart · tumor of the heart · tumour of heart · tumour of the heart

Disease family

This is a subtype of heart disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › cardiovascular disorder › heart disorder › heart neoplasm

Related subtypes (33): endocardium disorder, pericardium disorder, cardiac tuberculosis, heart conduction disease, hypertensive heart disease, heart valve disorder, cardiomyopathy, coronary artery disorder, heart failure, congenital heart disease, heart aneurysm, rheumatic heart disease, cardiac rhythm disease, white forelock with malformations, atrioventricular defect-blepharophimosis-radial and anal defect syndrome, microcephaly-cardiac defect-lung malsegmentation syndrome, PHACE syndrome, microcephaly-facio-cardio-skeletal syndrome, Hadziselimovic type, cardiac anomalies-heterotaxy syndrome, polyvalvular heart disease syndrome, Thomas syndrome, 22q11.2 deletion syndrome, myocardial rupture, aortopulmonary window, cor biloculare, inflammation of heart layer, myocardial disorder, carcinoid heart disease, omphalocele-diaphragmatic hernia-cardiovascular anomalies-radial ray defect syndrome, coronary microvascular disorder, cardiac ventricle disorder, cardiogenetic disease, cardiogenic shock

Subtypes (10): heart cancer, heart malignant hemangiopericytoma, familial atrial myxoma, primary adult heart tumor, primary pediatric heart tumor, cardiac germ cell tumor, neoplasm of endocardium, neoplasm of epicardium, neoplasm of myocardium, benign neoplasm of heart

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 8.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	7
PHASE4	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT05718128	PHASE4	RECRUITING	Clinical Study of Endocardial Myocardial Biopsy
NCT03444259	Not specified	ACTIVE_NOT_RECRUITING	Prospective Project to Identify Biomarkers of Morbidity and Mortality in Cardiovascular Interventional Patients
NCT06001073	Not specified	RECRUITING	Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics
NCT06100328	Not specified	RECRUITING	Characteristics of Cardiac Tumor and the Risk Stratification of Subsequent Adverse Events (UNIQUE)
NCT06830512	Not specified	RECRUITING	The Safety and Efficacy Evaluation of Echocardiography-guided Percutaneous Radiofrequency Ablation for Cardiac Tumors: a Single-arm, Prospective, Single-center Clinical Study
NCT02815553	Not specified	UNKNOWN	Cardiac Tumors Interventional （Radio Frequency/Laser Ablation）Therapy
NCT03377465	Not specified	COMPLETED	Biomarkers, Hemodynamic and Echocardiographic Predictors of Ischemic Strokes and Their Influence on the Course and Prognosis
NCT07132593	Not specified	COMPLETED	A Retrospective, Observational, and Descriptive Study of Pediatric Cardiac Fibroma