Herpesviridae infectious disease
diseaseOn this page
Also known as Herpesviridae caused disease or disorderHerpesviridae disease or disorderHerpesviridae infectionHerpesviridae infectionsHerpesvirus infectionHerpesvirus infectionsinfection, Herpesviridaeinfection, Herpesvirusinfections, Herpesviridaeinfections, Herpesvirus
Summary
Herpesviridae infectious disease (MONDO:0005794) is a disease (an umbrella term covering 8 Mondo subtypes) and 10 clinical trials. Top therapeutic interventions include ganciclovir and valacyclovir. A subtype of primary viral infectious disease — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Umbrella term: 8 Mondo subtypes
- Clinical trials: 10
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | Herpesviridae infectious disease |
| Mondo ID | MONDO:0005794 |
| EFO | EFO:0007309 |
| MeSH | D006566 |
| SNOMED CT | 23513009 |
| Is cancer (heuristic) | no |
Also known as: Herpesviridae caused disease or disorder · Herpesviridae disease or disorder · Herpesviridae infection · Herpesviridae infections · Herpesvirus infection · herpesvirus infection · Herpesvirus infections · infection, Herpesviridae · infection, Herpesvirus · infections, Herpesviridae · infections, Herpesvirus
Disease family
An umbrella term covering 8 Mondo subtypes.
Classification path: disease › human disease › disease by etiologic mechanism › disease of primarily extrinsic mechanism › infectious disease › viral infectious disease › primary viral infectious disease › Herpesviridae infectious disease
Related subtypes (31): plantar wart, monkeypox, smallpox, rubella, human papilloma virus infection, Rotavirus infection, Arenaviridae infectious disease, Astroviridae infectious disease, Caliciviridae infectious disease, cowpox, Flaviviridae infectious disease, Hepadnaviridae infectious disease, influenza, Mononegavirales infectious disease, Nidovirales infectious disease, phlebotomus fever, Picornaviridae infectious disease, polyomavirus infectious disease, Togaviridae infectious disease, viral encephalitis, viral hepatitis, viral pneumonia, viral exanthem, deltaretrovirus infections, Bunyaviridae infectious disease, viral sexually transmitted disease, lentivirus infection, viral myocarditis, viral pericarditis, adenoviridae infectious disease, aleutian mink disease, human
Subtypes (8): herpetic gastritis, herpes simplex infectious disease, Epstein-Barr virus infection, cytomegalovirus infection, human herpesvirus 8 infection, varicella zoster infection, roseolovirus infectious disease, congenital herpes virus infection
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 10.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 8 |
| PHASE4 | 2 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT00116844 | PHASE4 | COMPLETED | VALTREX Once Daily For Viral Shedding In Herpes Simplex Virus 2 (HSV-2) Seropositive Subjects. VALTREX® Tablet is a Trademark of GlaxoSmithKline Group of Companies. |
| NCT00373165 | PHASE4 | COMPLETED | Prophylaxis With Ganciclovir Improves Graft Survival in Renal Allograft Recipients |
| NCT05198570 | Not specified | RECRUITING | Pharmacokinetics of Intravenous Acyclovir in Oncologic Paediatric Patients |
| NCT00001156 | Not specified | COMPLETED | Assessment of Patients With Multiple Sclerosis (MS) |
| NCT00005496 | Not specified | COMPLETED | Inflammation, Infection, and Future Cardiovascular Risk |
| NCT00026728 | Not specified | COMPLETED | Seroprevalence of Kaposi’s Sarcoma Herpes Virus in the United States |
| NCT00228670 | Not specified | COMPLETED | Herpesvirus in Idiopathic Pulmonary Fibrosis |
| NCT01248598 | Not specified | UNKNOWN | The Prevelance Rate of Human Cytomegalovirus (HCMV), Epstein-Barr Virus (EBV) and Human Herpes Virus (HHV-6) in a Saliva of the Patient With Periodantitis |
| NCT03051789 | Not specified | COMPLETED | Cups or Cash for Girls Trial to Reduce Sexual and Reproductive Harm and School Dropout |
| NCT04412811 | Not specified | COMPLETED | Prospective Survey of CMV, Herpesviruses Infections and Diseases in Allo-HSCT |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| GANCICLOVIR | 4 | 1 |
| VALACYCLOVIR | 4 | 1 |
Related Atlas pages
- Drugs: Ganciclovir, Valacyclovir