Idiopathic catatonia
disease diseaseOn this page
Summary
Idiopathic catatonia (MONDO:0957487) is a disease. A subtype of catatonia — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Prevalence: <1 / 1 000 000 (Worldwide) [Orphanet-validated]
- Phenotypes (HPO): 16
Clinical features
Epidemiology
Prevalence records
2 prevalence record(s), Orphanet:
| Type | Class | Value | Geography | Validation |
|---|---|---|---|---|
| Cases/families | 16 | Worldwide | Validated | |
| Point prevalence | <1 / 1 000 000 | Worldwide | Validated |
Signs & symptoms
Clinical features (HPO)
16 HPO clinical features (Orphanet curated; top 16 by frequency):
| HPO ID | Term | Frequency |
|---|---|---|
| HP:0000273 | Facial grimacing | Frequent (30-79%) |
| HP:0000713 | Agitation | Frequent (30-79%) |
| HP:0000733 | Abnormal repetitive mannerisms | Frequent (30-79%) |
| HP:0001259 | Coma | Frequent (30-79%) |
| HP:0002039 | Anorexia | Frequent (30-79%) |
| HP:0002300 | Mutism | Frequent (30-79%) |
| HP:0002533 | Abnormal posturing | Frequent (30-79%) |
| HP:0007302 | Bipolar affective disorder | Frequent (30-79%) |
| HP:0010529 | Echolalia | Frequent (30-79%) |
| HP:0100753 | Schizophrenia | Frequent (30-79%) |
| HP:0410291 | Negativism | Frequent (30-79%) |
| HP:0000752 | Hyperactivity | Occasional (5-29%) |
| HP:0002396 | Cogwheel rigidity | Occasional (5-29%) |
| HP:0025401 | Staring gaze | Occasional (5-29%) |
| HP:0030903 | Grasp reflex | Occasional (5-29%) |
| HP:0100710 | Impulsivity | Occasional (5-29%) |
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | idiopathic catatonia |
| Mondo ID | MONDO:0957487 |
| Orphanet | 648919 |
| UMLS | C5816742 |
| MedGen | 1843416 |
| GARD | 0026851 |
| Is cancer (heuristic) | no |
Disease family
This is a subtype of catatonia. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by developmental or physiological process › psychiatric disorder › catatonia › idiopathic catatonia
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 0.
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.