Idiopathic panuveitis
diseaseOn this page
Summary
Idiopathic panuveitis (MONDO:0017258) is a disease. A subtype of panuveitis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Prevalence: 1-9 / 100 000 (Europe) [Orphanet-validated]
- Phenotypes (HPO): 19
Clinical features
Epidemiology
Prevalence records
4 prevalence record(s), Orphanet:
| Type | Class | Value | Geography | Validation |
|---|---|---|---|---|
| Annual incidence | 1-9 / 1 000 000 | 0.5051 | Europe | Validated |
| Point prevalence | 1-9 / 100 000 | 2.0194 | Europe | Validated |
| Annual incidence | 1-9 / 100 000 | 3.6 | United States | Validated |
| Point prevalence | 1-5 / 10 000 | 16 | United States | Validated |
Signs & symptoms
Clinical features (HPO)
19 HPO clinical features (Orphanet curated; top 19 by frequency):
| HPO ID | Term | Frequency |
|---|---|---|
| HP:0000504 | Abnormality of vision | Frequent (30-79%) |
| HP:0000622 | Blurred vision | Frequent (30-79%) |
| HP:0007663 | Reduced visual acuity | Frequent (30-79%) |
| HP:0025337 | Red eye | Frequent (30-79%) |
| HP:0030652 | Vitreous haze | Frequent (30-79%) |
| HP:0200026 | Ocular pain | Frequent (30-79%) |
| HP:0000518 | Cataract | Occasional (5-29%) |
| HP:0000613 | Photophobia | Occasional (5-29%) |
| HP:0000616 | Miosis | Occasional (5-29%) |
| HP:0002315 | Headache | Occasional (5-29%) |
| HP:0011484 | Posterior synechiae of the anterior chamber | Occasional (5-29%) |
| HP:0011505 | Cystoid macular edema | Occasional (5-29%) |
| HP:0030661 | Vitreous snowballs | Occasional (5-29%) |
| HP:0030953 | Conjunctival hyperemia | Occasional (5-29%) |
| HP:0100832 | Vitreous floaters | Occasional (5-29%) |
| HP:0000618 | Blindness | Very rare (<1-4%) |
| HP:0007906 | Ocular hypertension | Very rare (<1-4%) |
| HP:0011506 | Choroidal neovascularization | Very rare (<1-4%) |
| HP:0100014 | Epiretinal membrane | Very rare (<1-4%) |
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | idiopathic panuveitis |
| Mondo ID | MONDO:0017258 |
| Orphanet | 280921 |
| SNOMED CT | 766933000 |
| UMLS | C4707884 |
| MedGen | 1633708 |
| GARD | 0021100 |
| Is cancer (heuristic) | no |
Disease family
This is a subtype of panuveitis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › disorder of orbital region › eye disorder › uveal disorder › uveitis › panuveitis › idiopathic panuveitis
Related subtypes (3): infectious panuveitis, Vogt-Koyanagi-Harada disease, sympathetic ophthalmia
Subtypes (1): idiopathic uveal effusion syndrome
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 0.
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.