Immunotherapy induced hypophysitis

Summary

Immunotherapy induced hypophysitis (MONDO:0957423) is a disease. A subtype of hypophysitis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Prevalence: Unknown (Europe) [Orphanet-validated]

Clinical features

Epidemiology

Prevalence records

1 prevalence record(s), Orphanet:

Type	Class	Value	Geography	Validation
Annual incidence	1-5 / 10 000	12.8074	Europe	Validated

Identifiers

Disease identifiers

Field	Value
Canonical name	immunotherapy induced hypophysitis
Mondo ID	MONDO:0957423
Orphanet	641350
UMLS	C5816794
MedGen	1843401
GARD	0026823
Is cancer (heuristic)	no

Disease family

Classification path: disease › human disease › disease by body system or component › reproductive system disorder › pituitary gland disorder › hypophysitis › immunotherapy induced hypophysitis

Related subtypes (8): infundibulo-neurohypophysitis, lymphocytic hypophysitis, adenohypophysitis, panhypophysitis, granulomatous hypophysitis, xanthomatous hypophysitis, xanthogranulomatous hypophysitis, necrotizing hypophysitis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.