Indeterminate colitis
diseaseOn this page
Also known as colitis of indeterminate type
Summary
Indeterminate colitis (MONDO:0006038) is a disease and 20 clinical trials. Top therapeutic interventions include methylprednisolone. A subtype of colitis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 20
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | indeterminate colitis |
| Mondo ID | MONDO:0006038 |
| EFO | EFO:1000034 |
| ICD-10-CM | K52.3 |
| ICD-11 | 553916326 |
| NCIT | C27110 |
| SNOMED CT | 235746007 |
| UMLS | C0341332 |
| MedGen | 87418 |
| Is cancer (heuristic) | no |
Also known as: colitis of indeterminate type
Disease family
This is a subtype of colitis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › digestive system disorder › intestinal disorder › gastroenteritis › colitis › indeterminate colitis
Related subtypes (8): ischemic colitis, microscopic colitis, chemical colitis, diversion colitis, ulcerative colitis, ileocolitis, infectious colitis, proctocolitis
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 20.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 17 |
| PHASE3 | 1 |
| EARLY_PHASE1 | 1 |
| PHASE1 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT01692743 | PHASE3 | COMPLETED | Telemedicine in Patients With Inflammatory Bowel Disease (TELE-IBD) |
| NCT05587673 | PHASE1 | COMPLETED | High Dose Steroid Therapy to Treat Flares in Patients With Inflammatory Bowel Disease (IBD) |
| NCT03268213 | EARLY_PHASE1 | COMPLETED | Fecal Microbial Transplantation for C. Difficile and/or Ulcerative Colitis or Indeterminate Colitis |
| NCT00606346 | Not specified | ACTIVE_NOT_RECRUITING | A Multicenter, Prospective, Long-term, Observational Registry of Pediatric Patients With Inflammatory Bowel Disease |
| NCT03251118 | Not specified | ACTIVE_NOT_RECRUITING | A 5-year Longitudinal Observational Study of Patients Undergoing Therapy for Inflammatory Bowel Disease |
| NCT05704413 | Not specified | RECRUITING | Digestive Biobank for Exploring Microbiota-host Interactions |
| NCT06315179 | Not specified | RECRUITING | Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE) |
| NCT06655415 | Not specified | RECRUITING | Family Members At INcreased-risk for Developing Inflammatory Bowel Disease |
| NCT07195123 | Not specified | RECRUITING | Evaluation of the SMART IBD App in Pediatric IBD |
| NCT07237516 | Not specified | RECRUITING | Zymfentra (Infliximab-dyyb) REal World Cohort STudy |
| NCT07319442 | Not specified | RECRUITING | CEDUR - German IBD Registry |
| NCT01536509 | Not specified | COMPLETED | Improving Medication Adherence in Pediatric Inflammatory Bowel Disease |
| NCT01966744 | Not specified | COMPLETED | Self-Management Assistance for Recommended Treatment (SMART) Portal |
| NCT02066272 | Not specified | UNKNOWN | Safety of Anti-tumor Necrosis Factor (TNF) Monoclonal Antibodies in Inflammatory Bowel Disease |
| NCT03143517 | Not specified | COMPLETED | Fecal Calprotectin Collection Protocol |
| NCT03301311 | Not specified | COMPLETED | Personalized Research on Diet in Ulcerative Colitis and Crohn’s Disease |
| NCT04031482 | Not specified | UNKNOWN | TARGET Registry A Project of the German Network for Intestinal Diseases in Cooperation With Other Corporate Partners |
| NCT04191655 | Not specified | COMPLETED | High Definition Colonoscopy (HDC) vs. Dye Spraying Chromo-colonoscopy (DSC) in Screening Patients With Long-standing Inflammatory Bowel Disease (IBD) |
| NCT04672161 | Not specified | COMPLETED | Education Intervention on Vaccination Adherence Among Inflammatory Bowel Disease (IBD) Patients |
| NCT05663671 | Not specified | UNKNOWN | Evaluate Established Anti-DEFA5 mAbs Diagnostic Efficacy and Safety in IBD |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| METHYLPREDNISOLONE | 4 | 1 |
Related Atlas pages
- Drugs: Methylprednisolone