Infantile diarrhea

Summary

Infantile diarrhea (MONDO:0043555) is a disease and 5 clinical trials. A subtype of dysentery — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 5

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	infantile diarrhea
Mondo ID	MONDO:0043555
MeSH	D003968
SNOMED CT	39963006
UMLS	C0011992
MedGen	8361
Is cancer (heuristic)	no

Also known as: diarrheal disease of infancy · Diarrheas, infantile · infantile diarrhea · infantile diarrheal disease · infantile Diarrheas · infantile onset diarrheal disease · toddler diarrhea · toddler diarrhoea

Disease family

This is a subtype of dysentery. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › digestive system disorder › gastrointestinal mucositis › inflammatory diarrhea › dysentery › infantile diarrhea

Related subtypes (2): protozoal dysentery, shigellosis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

Drugs indicated for this disease

0 approved, 1 in late-stage (phase 3) trials. Disease-direct ChEMBL indications, not inferred from the associated-gene cohort below.

Drug	Development status
Racecadotril	Phase 3 (in late-stage trials)

Clinical trials & evidence

Clinical trials

Clinical trials: 5.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	4
PHASE4	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT01469273	PHASE4	UNKNOWN	Prophylaxis of Gastrointestinal Infections With EcN
NCT07444008	Not specified	RECRUITING	Randomized, Blinded, Placebo-Controlled Evaluation of BioAmicus Complete
NCT01612572	Not specified	UNKNOWN	A Registry Study on Xiyanping(a Chinese Medicine Injection) Used in Fifty Hospitals
NCT02870491	Not specified	COMPLETED	Working With Community Health Workers to Increase ORS Use in Uganda
NCT04262648	Not specified	COMPLETED	Randomized Placebo-controlled Study of L. Reuteri NCIMB 30351 in GI Functional Disorders and Food Allergy in Newborns