Infectious peritonitis

Summary

Infectious peritonitis (MONDO:0004522) is a disease and 7 clinical trials. A subtype of infectious disease — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 7

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	infectious peritonitis
Mondo ID	MONDO:0004522
EFO	EFO:0008588
DOID	DOID:8283
ICD-10-CM	K65
NCIT	C26849
SNOMED CT	86422009
UMLS	C1264610
MedGen	688825
Is cancer (heuristic)	no

Also known as: acute generalised peritonitis

Disease family

This is a subtype of infectious disease. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › disease of primarily extrinsic mechanism › infectious disease › infectious peritonitis

Related subtypes (34): infective endocarditis, hirudiniasis, fungal infectious disease, epididymitis, viral infectious disease, bacterial infectious disease, parasitic infectious disease, abscess, Ciliophora infectious disease, hookworm infectious disease, infectious embryofetopathy, mycetoma, infectious disorder of the nervous system, ear infection, sexually transmitted disease, puerperal infection, Acanthamoeba infectious disease, infectious myositis, infective vaginitis, skin disorder caused by infection, respiratory tract infectious disorder, nail infection, infective arthritis, digestive system infectious disorder, nosocomial infection, eye infectious disorder, prosthesis-related infectious disease, vector-borne disease, coinfection, urinary tract infection, hemorrhagic fever, protothecosis, pythiosis, infectious disease with sepsis

Subtypes (3): diphtheritic peritonitis, septic peritonitis, tuberculous peritonitis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

Drugs indicated for this disease

3 approved, 10 in late-stage (phase 3) trials. Disease-direct ChEMBL indications, not inferred from the associated-gene cohort below.

Drug	Development status
Anidulafungin	Approved (phase 4)
Ceftazidime	Approved (phase 4)
Clindamycin Phosphate	Approved (phase 4)
Cefotaxime	Phase 3 (in late-stage trials)
Ceftriaxone	Phase 3 (in late-stage trials)
Ciprofloxacin	Phase 3 (in late-stage trials)
Co-Trimoxazole	Phase 3 (in late-stage trials)
Doripenem	Phase 3 (in late-stage trials)
Gemifloxacin	Phase 3 (in late-stage trials)
Itopride	Phase 3 (in late-stage trials)
Nitazoxanide	Phase 3 (in late-stage trials)
Norfloxacin	Phase 3 (in late-stage trials)
Rifaximin	Phase 3 (in late-stage trials)

Clinical trials & evidence

Clinical trials

Clinical trials: 7.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	6
PHASE4	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT02940730	PHASE4	COMPLETED	Evaluation of Intravenous and Intraperitoneal Pharmacokinetics of Dalbavancin in Peritoneal Dialysis Patients
NCT07232342	Not specified	RECRUITING	Capillary Leak Index Versus Conventional Biomarkers in Predicting Sepsis-Related Outcomes
NCT07429929	Not specified	NOT_YET_RECRUITING	Saudi Emergency Laparotomy Audit
NCT03140748	Not specified	COMPLETED	Kinetics of Serum β-D-glucan During Peritonitis With Candida in Resuscitation
NCT05264571	Not specified	COMPLETED	Early Identification of Candida in Intra-abdominal Candidiasis
NCT07005258	Not specified	COMPLETED	Diagnostic Performance of the CandID PLUS PCR for the Diagnosis of Intra-abdominal Candidiasis in Critically Ill Patients
NCT07562204	Not specified	COMPLETED	Rapid Identification of Microbial Pathogens in Intra-abdominal Infections Using Multiplex PCR