Infertility due to extratesticular cause

Summary

Infertility due to extratesticular cause (MONDO:0001877) is a disease. A subtype of male infertility — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	infertility due to extratesticular cause
Mondo ID	MONDO:0001877
DOID	DOID:14096
SNOMED CT	84245004
UMLS	C0021360
MedGen	507846
Is cancer (heuristic)	no

Also known as: infertility due to extratesticular causes

Disease family

This is a subtype of male infertility. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › reproductive system disorder › male reproductive system disorder › male infertility › infertility due to extratesticular cause

Related subtypes (7): oligospermia, spermatogenic failure, partial chromosome Y deletion, male infertility with teratozoospermia due to single gene mutation, male infertility due to acephalic spermatozoa, azoospermia, oligoasthenoteratozoospermia

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.