Inhalational botulism
diseaseOn this page
Also known as inhalation botulism
Summary
Inhalational botulism (MONDO:0016777) is a disease. A subtype of botulism — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Prevalence: <1 / 1 000 000 (Worldwide) [Orphanet-validated]
- Phenotypes (HPO): 13
Clinical features
Epidemiology
Prevalence records
2 prevalence record(s), Orphanet:
| Type | Class | Value | Geography | Validation |
|---|---|---|---|---|
| Cases/families | 10 | Worldwide | Validated | |
| Point prevalence | <1 / 1 000 000 | Worldwide | Validated |
Signs & symptoms
Clinical features (HPO)
13 HPO clinical features (Orphanet curated; top 13 by frequency):
| HPO ID | Term | Frequency |
|---|---|---|
| HP:0000016 | Urinary retention | Very frequent (80-99%) |
| HP:0000217 | Xerostomia | Very frequent (80-99%) |
| HP:0000508 | Ptosis | Very frequent (80-99%) |
| HP:0000651 | Diplopia | Very frequent (80-99%) |
| HP:0001324 | Muscle weakness | Very frequent (80-99%) |
| HP:0002019 | Constipation | Very frequent (80-99%) |
| HP:0003470 | Paralysis | Very frequent (80-99%) |
| HP:0006824 | Cranial nerve paralysis | Very frequent (80-99%) |
| HP:0011499 | Mydriasis | Very frequent (80-99%) |
| HP:0012378 | Fatigue | Very frequent (80-99%) |
| HP:0002014 | Diarrhea | Frequent (30-79%) |
| HP:0002017 | Nausea and vomiting | Frequent (30-79%) |
| HP:0002094 | Dyspnea | Frequent (30-79%) |
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | inhalational botulism |
| Mondo ID | MONDO:0016777 |
| Orphanet | 254504 |
| ICD-11 | 1881625139 |
| SNOMED CT | 409562009 |
| UMLS | C1443900 |
| MedGen | 731169 |
| GARD | 0020746 |
| Is cancer (heuristic) | no |
Also known as: inhalation botulism
Disease family
This is a subtype of botulism. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by etiologic mechanism › disease of primarily extrinsic mechanism › infectious disease › bacterial infectious disease › primary bacterial infectious disease › botulism › inhalational botulism
Related subtypes (3): foodborne botulism, toxin-mediated infectious botulism, iatrogenic botulism
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 0.
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.