Interstitial emphysema

Summary

Interstitial emphysema (MONDO:0000923) is a disease and 1 clinical trial. A subtype of pulmonary emphysema — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 1

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	interstitial emphysema
Mondo ID	MONDO:0000923
DOID	DOID:10030
ICD-10-CM	J98.2
ICD-11	2008095771
NCIT	C34571
SNOMED CT	77690003
UMLS	C1370824
MedGen	234586
Is cancer (heuristic)	no

Also known as: interstitial emphysema of lung · PIE · pie · pulmonary interstitial emphysema

Disease family

This is a subtype of pulmonary emphysema. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › respiratory system disorder › lower respiratory tract disorder › lung disorder › obstructive lung disease › chronic obstructive pulmonary disease › pulmonary emphysema › interstitial emphysema

Related subtypes (4): compensatory emphysema, hyperlucent lung, emphysema, hereditary pulmonary, congenital lobar emphysema

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 1.

Phase distribution (across all retrieved trials)

Phase	Trials
PHASE4	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT01329432	PHASE4	UNKNOWN	Surfactant Administration During Spontaneous Breathing