Intestinal helminthiasis

disease
On this page

Also known as intestine parasitic helminthiasis infectious disease

Summary

Intestinal helminthiasis (MONDO:0024271) is a disease and 6 clinical trials. Top therapeutic interventions include albendazole, ascorbic acid, and praziquantel. A subtype of helminthiasis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

  • Clinical trials: 6

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

FieldValue
Canonical nameintestinal helminthiasis
Mondo IDMONDO:0024271
MeSHC531698
SNOMED CT26249004
UMLSC0348287
MedGen87591
Anatomy (UBERON)UBERON:0000160
Is cancer (heuristic)no

Also known as: intestine parasitic helminthiasis infectious disease

Disease family

This is a subtype of helminthiasis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › disease of primarily extrinsic mechanism › infectious diseaseparasitic infectious diseasehelminthiasisintestinal helminthiasis

Related subtypes (21): acanthocephaliasis, heterophyiasis, metagonimiasis, fascioliasis, fasciolopsiasis, monieziasis, clonorchiasis, dicrocoeliasis, echinostomiasis, fascioloidiasis, gnathomiasis, hymenolepiasis, necatoriasis, Nematoda infectious disease, opisthorchiasis, paragonimiasis, trichostrongyloidiasis, schistosomiasis, filariasis, angiostrongyliasis, Cestode infectious disease

Subtypes (3): taeniasis, intestinal schistosomiasis, anisakiasis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 6.

Phase distribution (across all retrieved trials)

PhaseTrials
Not specified4
PHASE41
PHASE11

Top trials by phase / activity

NCTPhaseStatusTitle
NCT02597556PHASE4WITHDRAWNThe Impact of Anthelmintic Treatment on the Incidence of Diarrheal Disease in Vietnamese School Children
NCT01640626PHASE1COMPLETEDImpact of Health Education on School Children
NCT01541631Not specifiedUNKNOWNA Study of Co-infections of HIV-1 and Schistosoma Mansoni and Its Impact on Praziquantel Treatment Outcomes
NCT01658774Not specifiedCOMPLETEDImpact of Repeated Anthelmintic Treatment on the Risk of Malaria in Kenyan School Children
NCT02399683Not specifiedCOMPLETEDImmune Modulation From Trichuris Trichiura
NCT03079700Not specifiedCOMPLETEDImmune Modulation From Trichuris Suis

Drugs tested across these trials (top 30)

MoleculeMax phaseTrials referencing
ALBENDAZOLE43
ASCORBIC ACID41
PRAZIQUANTEL41
CHEMBL326424501