Intestinal volvulus

disease
On this page

Also known as volvulus

Summary

Intestinal volvulus (MONDO:0004570) is a disease and 6 clinical trials. Top therapeutic interventions include indocyanine green acid form. A subtype of intestinal obstruction — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

  • Clinical trials: 6

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

FieldValue
Canonical nameintestinal volvulus
Mondo IDMONDO:0004570
MeSHD045822
DOIDDOID:8445
ICD-10-CMK56.2
SNOMED CT9707006
UMLSC0042961
MedGen21892
Is cancer (heuristic)no

Also known as: volvulus

Disease family

This is a subtype of intestinal obstruction. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › digestive system disorderintestinal disorderintestinal obstructionintestinal volvulus

Related subtypes (5): duodenal obstruction, ileus, intestinal impaction, intussusception, encapsulating peritoneal sclerosis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 6.

Phase distribution (across all retrieved trials)

PhaseTrials
Not specified6

Top trials by phase / activity

NCTPhaseStatusTitle
NCT01301417Not specifiedCOMPLETEDData Collection of Patients Treated With the ColonRing™ for the Creation of Circular Compression Anastomosis
NCT01682395Not specifiedCOMPLETEDBest Management of Sigmoid Volvulus: A Prospective Randomized Trial
NCT01880918Not specifiedUNKNOWNA RETROspective Data Collection of comPRESSion Anastomosis Using the ColonRing
NCT04020939Not specifiedCOMPLETEDThe Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery.
NCT05293353Not specifiedUNKNOWNNeokare Safety and Tolerability Assessment in Neonates With GI Problems
NCT06958900Not specifiedCOMPLETEDEffect of Malignancy on Morbidity and Mortality in Left-sided Emergency Colorectal Resections

Drugs tested across these trials (top 30)

MoleculeMax phaseTrials referencing
INDOCYANINE GREEN ACID FORM41