Intracranial arterial disease

Summary

Intracranial arterial disease (MONDO:0006808) is a disease and 6 clinical trials. A subtype of cerebrovascular disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 6

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	intracranial arterial disease
Mondo ID	MONDO:0006808
EFO	EFO:1000990
MeSH	D020765
DOID	DOID:13089
UMLS	C0752138
MedGen	199819
Is cancer (heuristic)	no

Disease family

This is a subtype of cerebrovascular disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › nervous system disorder › central nervous system disorder › brain disorder › cerebrovascular disorder › intracranial arterial disease

Related subtypes (23): cerebral arteritis, intracranial thrombosis, occlusion precerebral artery, vascular dementia, stroke disorder, internal carotid artery stenosis, carotid artery disorder, brain ischemia, brain infarction, cerebral amyloid angiopathy, vascular brain injury, basal ganglia cerebrovascular disorder, intracranial vasospasm, subclavian steal syndrome, pseudotumor cerebri, cerebral sinovenous thrombosis, HTRA1-related autosomal dominant cerebral small vessel disease, familial porencephaly, microangiopathy and leukoencephalopathy, pontine, autosomal dominant, cathepsin a-related arteriopathy-strokes-leukoencephalopathy, precerebral artery stenosis, cerebral artery stenosis, APP-related brain and vascular amyloidosis

Subtypes (1): cerebral arterial disease

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 6.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	6

Top trials by phase / activity

NCT	Phase	Status	Title
NCT07353736	Not specified	NOT_YET_RECRUITING	Cerebral Arteriovenous Malformation With Aneurysm: Epidemiology, Clinical Features, and Prognosis
NCT00703794	Not specified	COMPLETED	Researching AXIUM Coiling Experience and Recanalization (RACER)
NCT02341794	Not specified	UNKNOWN	Rosuvastatin Treatment for Intracranial Arterial Stenosis Based on Magnetic Resonance Angiography
NCT03916133	Not specified	COMPLETED	Analysis of Selective Cerebrovascular Distribution With FDCT in the Angiosuite
NCT05063630	Not specified	UNKNOWN	Intracranial Stenting in Non-acute Symptomatic Ischemic Stroke
NCT05217459	Not specified	COMPLETED	The Efficacy and Safety of Intracranial Self-expanding DES in Symptomatic Intracranial Atherosclerotic Disease

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
CHEMBL1357356	0	1