Intracranial primitive neuroectodermal tumor

Summary

Intracranial primitive neuroectodermal tumor (MONDO:0003142) is a cancer. A subtype of central nervous system primitive neuroectodermal neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	intracranial primitive neuroectodermal tumor
Mondo ID	MONDO:0003142
DOID	DOID:4788
NCIT	C5817
UMLS	C0346292
MedGen	577349
GARD	0027631
Anatomy (UBERON)	UBERON:0000955
Is cancer (heuristic)	yes

Also known as: brain primitive neuroectodermal tumor · brain primitive neuroectodermal tumour · intracranial primitive neuroectodermal neoplasm · primitive neuroectodermal tumor of brain · primitive neuroectodermal tumour of brain

Disease family

This is a subtype of central nervous system primitive neuroectodermal neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › cancer › nervous system cancer › central nervous system cancer › central nervous system primitive neuroectodermal neoplasm › intracranial primitive neuroectodermal tumor

Related subtypes (7): adult central nervous system primitive neuroectodermal neoplasm, childhood central nervous system primitive neuroectodermal neoplasm, spinal cord neuroblastoma, ganglioneuroma, spinal cord primitive neuroectodermal tumor, ependymoblastoma, central nervous system tumor with bcor internal tandem duplication

Subtypes (4): cerebral neuroblastoma, pediatric infratentorial ependymoblastoma, pediatric cerebral ependymoblastoma, olfactory neuroblastoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.