Intraductal breast papilloma

Summary

Intraductal breast papilloma (MONDO:0021097) is a disease (an umbrella term covering 5 Mondo subtypes) and 2 clinical trials. A subtype of breast benign neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Umbrella term: 5 Mondo subtypes
• Clinical trials: 2

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	intraductal breast papilloma
Mondo ID	MONDO:0021097
DOID	DOID:1626
NCIT	C3863
SNOMED CT	254848002, 99571000119102
UMLS	C0238034
MedGen	65944
Anatomy (UBERON)	UBERON:0001765
Is cancer (heuristic)	no

Also known as: breast papilloma · duct papilloma of breast · duct papilloma of the breast · ductal breast papilloma · intraductal breast papilloma · intraductal papilloma of breast · intraductal papilloma of the breast · mammary duct papilloma · papilloma of breast · papilloma of the breast

Disease family

This is a subtype of breast benign neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › benign neoplasm › thoracic benign neoplasm › breast benign neoplasm › intraductal breast papilloma

Related subtypes (14): breast lipoma, breast cyst, benign eccrine breast spiradenoma, breast fibroadenoma, breast leiomyoma, breast adenoma, breast myofibroblastoma, benign breast adenomyoepithelioma, breast hemangioma, multiple fibroadenoma of the breast, benign breast phyllodes tumor, benign neoplasm of male breast, diabetic mastopathy, lymphocytic mastitis

Subtypes (5): intracystic papillary adenoma, sclerosing breast papilloma, central breast papilloma, microscopic breast papilloma, atypical breast papilloma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 2.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	2

Top trials by phase / activity

NCT	Phase	Status	Title
NCT01901562	Not specified	TERMINATED	Feasibility and Therapeutic Efficacy of Ductoscopic Papilloma Extraction in Patients With Pathologic Nipple Discharge
NCT03868475	Not specified	WITHDRAWN	Comparing Vacuum-Assisted Percutaneous Excision to Open Surgical Excision for Borderline or High-Risk Breast Lesions