Inverted papilloma

Summary

Inverted papilloma (MONDO:0002537) is a disease (an umbrella term covering 5 Mondo subtypes) and 2 clinical trials. A subtype of papilloma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Umbrella term: 5 Mondo subtypes
• Clinical trials: 2

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	inverted papilloma
Mondo ID	MONDO:0002537
MeSH	D018308
DOID	DOID:3179
NCIT	C3793
SNOMED CT	104081000119103
UMLS	C0206721
MedGen	61668
Is cancer (heuristic)	no

Also known as: inverted papilloma

Disease family

This is a subtype of papilloma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › epithelial neoplasm › papillary epithelial neoplasm › papilloma › inverted papilloma

Related subtypes (13): squamous papilloma, intraductal papilloma, serous surface papilloma, fallopian tube papilloma, verrucous papilloma, skin papilloma, cervical mullerian papilloma, transitional cell papilloma, lung papilloma, choroid plexus papilloma, glandular papilloma, papilloma of buccal mucosa, laryngeal papillomatosis

Subtypes (5): inverted transitional cell papilloma, ethmoid sinus inverted papilloma, sphenoid sinus inverted papilloma, maxillary sinus inverted papilloma, frontal sinus inverted papilloma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 2.

Phase distribution (across all retrieved trials)

Phase	Trials
PHASE1	1
Not specified	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT03925285	PHASE1	UNKNOWN	Image Guided Surgery in Sinonasal Inverted Papilloma
NCT05363423	Not specified	UNKNOWN	Lateral Pedicled Nasoseptal Flaps for Endoscopic Draf III Procedure in Patients With Frontal Sinus Inverted Papilloma