Irritant dermatitis

Summary

Irritant dermatitis (MONDO:0006564) is a disease and 8 clinical trials. A subtype of contact dermatitis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 8

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	irritant dermatitis
Mondo ID	MONDO:0006564
EFO	EFO:1000718
MeSH	D017453
DOID	DOID:2772
ICD-10-CM	L24
NCIT	C27151
SNOMED CT	110979008
UMLS	C0162823
MedGen	56513
Is cancer (heuristic)	no

Also known as: irritant contact dermatitis

Disease family

This is a subtype of contact dermatitis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › integumentary system disorder › skin disorder › dermatitis › contact dermatitis › irritant dermatitis

Related subtypes (3): contact dermatitis due to nickel, allergic contact dermatitis, occupational dermatitis

Subtypes (1): phototoxic dermatitis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 8.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	8

Top trials by phase / activity

NCT	Phase	Status	Title
NCT06178289	Not specified	ENROLLING_BY_INVITATION	Effectiveness of 3M Cavilon Advanced Skin Protectant in the Treatment of Moisture-associated Skin Damage in Hospitals
NCT07286487	Not specified	NOT_YET_RECRUITING	Glycyrrhetinic Acid and Acute Irritant Dermatitis
NCT07524439	Not specified	NOT_YET_RECRUITING	Improving the Care of Incontinence-Associated Dermatitis (IAD) Using a Beta-Glucan Cream as a Hydrating and Soothing Agent
NCT02996357	Not specified	COMPLETED	Risk Factors for Incontinence-Associated Dermatitis (IAD) in ICU Patients Suffering From Fecal Incontinence
NCT03231813	Not specified	COMPLETED	Regional Differences of Cutaneous Irritation and Its Effect on Skin Barrier Recovery
NCT03483025	Not specified	COMPLETED	Prospective Single Center Randomized Double Blind Controlled Tolerability Trial of Six Hair Cleansing Conditioners
NCT03685929	Not specified	COMPLETED	Histopathological Comparison Between Superficial Pressure Ulcers and Incontinence-associated Dermatitis
NCT04793711	Not specified	TERMINATED	EpiCeram for Skin Protection in Healthcare Workers