isolated optic neuritis with anti-MOG antibodies

Summary

isolated optic neuritis with anti-MOG antibodies (MONDO:0035668) is a disease. A subtype of isolated optic neuritis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	isolated optic neuritis with anti-MOG antibodies
Mondo ID	MONDO:0035668
Orphanet	592888
GARD	0022377
Is cancer (heuristic)	no

Also known as: Isolated optic neuritis with anti-myelin oligodendrocyte glycoprotein antibodies

Disease family

This is a subtype of isolated optic neuritis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › disorder of orbital region › eye disorder › autoimmune/inflammatory optic neuropathy › isolated optic neuritis › isolated optic neuritis with anti-MOG antibodies

Related subtypes (3): isolated optic neuritis without anti-MOG antibodies, single isolated optic neuritis, relapsing isolated optic neuritis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.