Jaw fracture

Summary

Jaw fracture (MONDO:0100075) is a disease and 4 clinical trials. A subtype of bone fracture — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 4

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	jaw fracture
Mondo ID	MONDO:0100075
EFO	EFO:0009612
MeSH	D007572
Is cancer (heuristic)	no

Also known as: lower jaw fracture · upper jaw fracture

Disease family

This is a subtype of bone fracture. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: injury › bone fracture › jaw fracture

Related subtypes (6): spinal fracture, humerus fracture, tibia fracture, ulna fracture, radius fracture, hip fracture

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 4.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	2
PHASE3	1
PHASE1	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT06773923	PHASE3	ENROLLING_BY_INVITATION	Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration
NCT04198129	PHASE1	TERMINATED	The Evaluation of Postoperative Antibiotics in Non-Infected Mandible Fractures
NCT02293031	Not specified	UNKNOWN	Gene-activated Matrix for Bone Tissue Repair in Maxillofacial Surgery
NCT04985461	Not specified	COMPLETED	Minimally Invasive Dental Occlusion Ties

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
CHEMBL443232	0	1