Juvenile temporal arteritis
disease diseaseOn this page
Also known as JGCAJPMRJTAjuvenile cranial arteritisjuvenile giant cell arteritisjuvenile polymyalgia rheumaticanon-giant cell granulomatous temporal arteritis with eosinophilia
Summary
Juvenile temporal arteritis (MONDO:0016848) is a disease. A subtype of arteritis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Prevalence: <1 / 1 000 000 (Worldwide) [Orphanet-validated]
- Phenotypes (HPO): 8
Clinical features
Epidemiology
Prevalence records
2 prevalence record(s), Orphanet:
| Type | Class | Value | Geography | Validation |
|---|---|---|---|---|
| Cases/families | 20 | Worldwide | Validated | |
| Point prevalence | <1 / 1 000 000 | Worldwide | Validated |
Signs & symptoms
Clinical features (HPO)
8 HPO clinical features (Orphanet curated; top 8 by frequency):
| HPO ID | Term | Frequency |
|---|---|---|
| HP:0001974 | Leukocytosis | Frequent (30-79%) |
| HP:0002315 | Headache | Frequent (30-79%) |
| HP:0200036 | Skin nodule | Frequent (30-79%) |
| HP:0000509 | Conjunctivitis | Occasional (5-29%) |
| HP:0001880 | Eosinophilia | Occasional (5-29%) |
| HP:0003193 | Allergic rhinitis | Occasional (5-29%) |
| HP:0002633 | Vasculitis | Excluded (0%) |
| HP:0002637 | Cerebral ischemia | Excluded (0%) |
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | juvenile temporal arteritis |
| Mondo ID | MONDO:0016848 |
| Orphanet | 26137 |
| ICD-11 | 135739104 |
| SNOMED CT | 722020006 |
| UMLS | C0751547 |
| MedGen | 155583 |
| GARD | 0003068 |
| Is cancer (heuristic) | no |
Also known as: JGCA · JPMR · JTA · juvenile cranial arteritis · juvenile giant cell arteritis · juvenile polymyalgia rheumatica · non-giant cell granulomatous temporal arteritis with eosinophilia
Disease family
This is a subtype of arteritis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › cardiovascular disorder › vascular disorder › arterial disorder › arteritis › juvenile temporal arteritis
Related subtypes (6): cerebral arteritis, granulomatous angiitis, Takayasu arteritis, microscopic polyangiitis, polyarteritis nodosa, endarteritis
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 0.
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.