Juxtacortical osteosarcoma

Summary

Juxtacortical osteosarcoma (MONDO:0006817) is a disease and 2 clinical trials. A subtype of peripheral osteosarcoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 2

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	juxtacortical osteosarcoma
Mondo ID	MONDO:0006817
EFO	EFO:1001000
MeSH	D018217
DOID	DOID:3373
NCIT	C8969
UMLS	C0206642
MedGen	60197
GARD	0024479
Is cancer (heuristic)	no

Also known as: juxtacortical osteogenic sarcoma · juxtacortical osteosarcoma · PAOS · parosteal osteogenic sarcoma · parosteal osteosarcoma

Disease family

This is a subtype of peripheral osteosarcoma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › cancer › sarcoma › osteosarcoma › bone osteosarcoma › peripheral osteosarcoma › juxtacortical osteosarcoma

Related subtypes (2): periosteal osteogenic sarcoma, high grade surface osteosarcoma

Subtypes (1): childhood parosteal osteosarcoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 2.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	2

Top trials by phase / activity

NCT	Phase	Status	Title
NCT05515068	Not specified	NOT_YET_RECRUITING	Registry For Children, Adolescents And Adults With Osteosarcoma And Biologically Related Bone Sarcomas
NCT03768076	Not specified	COMPLETED	an Istitution Experience on Parosteal OsTeosarcoma