Kerion celsi

Summary

Kerion celsi (MONDO:0010146) is a disease and 1 clinical trial. Top therapeutic interventions include hyoscyamine. A subtype of dermatophytosis of scalp or beard — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Prevalence: Unknown (Worldwide)
• Phenotypes (HPO): 8
• Clinical trials: 1

Clinical features

Signs & symptoms

Clinical features (HPO)

8 HPO clinical features (Orphanet curated; top 8 by frequency):

HPO ID	Term	Frequency
HP:0001581	Recurrent skin infections	Very frequent (80-99%)
HP:0011123	Inflammatory abnormality of the skin	Very frequent (80-99%)
HP:0100838	Recurrent cutaneous abscess formation	Very frequent (80-99%)
HP:0001596	Alopecia	Frequent (30-79%)
HP:0001945	Fever	Frequent (30-79%)
HP:0002716	Lymphadenopathy	Frequent (30-79%)
HP:0002076	Migraine	Occasional (5-29%)
HP:0003326	Myalgia	Occasional (5-29%)

Identifiers

Disease identifiers

Field	Value
Canonical name	Kerion celsi
Mondo ID	MONDO:0010146
OMIM	275240
Orphanet	499
ICD-11	1449494917
SNOMED CT	19087001
UMLS	C0276742
MedGen	124446
GARD	0003109
Is cancer (heuristic)	no

Also known as: susceptibility to Tinea imbricata · Tinea capitis profunda · trichophytia profunda barbae · trichophytia profunda capitis · Trichophyton infection

Disease family

This is a subtype of dermatophytosis of scalp or beard. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › disease of primarily extrinsic mechanism › infectious disease › fungal infectious disease › cutaneous mycosis › tinea infection › dermatophytosis › dermatophytosis of scalp or beard › Kerion celsi

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 1.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT07420894	Not specified	COMPLETED	Comparison of Combination of Itraconazole and Isotretinoin Versus Itraconazole Alone in the Treatment of Resistant Trichophyton Infection

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
HYOSCYAMINE	-1	1