Larynx squamous papilloma
disease diseaseOn this page
Also known as laryngeal papillomalarynx papillomapapilloma of larynxpapilloma of the larynxsquamous papilloma of larynxsquamous papilloma of the larynx
Summary
Larynx squamous papilloma (MONDO:0000935) is a disease and 3 clinical trials. Top therapeutic interventions include celecoxib, human papillomavirus, l1 protein virus like particles, and curcumin. A subtype of squamous papilloma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 3
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | larynx squamous papilloma |
| Mondo ID | MONDO:0000935 |
| DOID | DOID:10071 |
| NCIT | C7742 |
| UMLS | C0240164 |
| MedGen | 116099 |
| Anatomy (UBERON) | UBERON:0001737 |
| Is cancer (heuristic) | no |
Also known as: laryngeal papilloma · larynx papilloma · larynx squamous papilloma · papilloma of larynx · papilloma of the larynx · squamous papilloma of larynx · squamous papilloma of the larynx
Disease family
This is a subtype of squamous papilloma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › epithelial neoplasm › papillary epithelial neoplasm › papilloma › squamous papilloma › larynx squamous papilloma
Related subtypes (7): bladder squamous papilloma, vaginal squamous papilloma, vestibular papilloma, nasal vestibule squamous papilloma, squamous cell skin papilloma, cervix squamous papilloma, esophagus squamous cell papilloma
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 3.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| PHASE3 | 1 |
| PHASE2 | 1 |
| PHASE1/PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT01375868 | PHASE3 | COMPLETED | Effect of Vaccination in Patients With Recurrent Respiratory Papillomatosis |
| NCT05688488 | PHASE1/PHASE2 | RECRUITING | Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal Cords |
| NCT00592319 | PHASE2 | TERMINATED | Celebrex (Celecoxib) Treatment of Laryngeal Papilloma |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| CELECOXIB | 4 | 1 |
| HUMAN PAPILLOMAVIRUS, L1 PROTEIN VIRUS LIKE PARTICLES | 4 | 1 |
| CURCUMIN | 3 | 1 |