Linear and whorled nevoid hypermelanosis
disease diseaseOn this page
Also known as Becker NevusBecker's Nevuslinear and whorled hypermelanosislinear papular ectodermal-mesodermal hamartomaLWNHmelanosis Neviformisnevoid hypermelanosis, linear and whorledpigmented hairy Epidermal Nevuspigmented hairy Nevus of Beckerprogressive cribriform and zosteriform hyperpigmentationreticulate hyperpigmentation of Iijimazebra-like hyperpigmentationzosteriform hyperpigmentationzosteriform lentiginous nevus
Summary
Linear and whorled nevoid hypermelanosis (MONDO:0013688) is a disease. A subtype of hamartoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Prevalence: <1 / 1 000 000 (Worldwide) [Orphanet-validated]
Clinical features
Epidemiology
Prevalence records
2 prevalence record(s), Orphanet:
| Type | Class | Value | Geography | Validation |
|---|---|---|---|---|
| Cases/families | 16 | Worldwide | Validated | |
| Point prevalence | <1 / 1 000 000 | Worldwide | Validated |
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | linear and whorled nevoid hypermelanosis |
| Mondo ID | MONDO:0013688 |
| OMIM | 614323 |
| Orphanet | 79150 |
| NCIT | C3924 |
| SNOMED CT | 403803002 |
| UMLS | C1304501 |
| MedGen | 473394 |
| GARD | 0011004 |
| Is cancer (heuristic) | no |
Also known as: Becker Nevus · Becker’s Nevus · linear and whorled hypermelanosis · linear papular ectodermal-mesodermal hamartoma · LWNH · melanosis Neviformis · nevoid hypermelanosis, linear and whorled · pigmented hairy Epidermal Nevus · pigmented hairy Nevus of Becker · progressive cribriform and zosteriform hyperpigmentation · reticulate hyperpigmentation of Iijima · zebra-like hyperpigmentation · zosteriform hyperpigmentation · zosteriform lentiginous nevus
Disease family
This is a subtype of hamartoma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › hamartoma › linear and whorled nevoid hypermelanosis
Related subtypes (12): chondroid hamartoma, gastrointestinal hamartoma, linear nevus sebaceous syndrome, congenital epulis, congenital smooth muscle hamartoma, hamartoma of skin appendage, hamartoma of lung, basaloid follicular hamartoma, angiomyomatous hamartoma, giant mammary hamartoma, mesenchymal hamartoma, odontoma
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 0.
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.