Liver lymphoma
diseaseOn this page
Also known as hepatic lymphomalymphoma of liverlymphoma of the liverprimary hepatic lymphomaprimary liver lymphoma
Summary
Liver lymphoma (MONDO:0004695) is a cancer and 1 clinical trial. Top therapeutic interventions include acalabrutinib, bendamustine, and rituximab. A subtype of liver cancer — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Classification: Cancer
- Clinical trials: 1
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | liver lymphoma |
| Mondo ID | MONDO:0004695 |
| DOID | DOID:901 |
| NCIT | C4949 |
| UMLS | C1112746 |
| MedGen | 207276 |
| GARD | 0024089 |
| Anatomy (UBERON) | UBERON:0002107 |
| Is cancer (heuristic) | yes |
Also known as: hepatic lymphoma · liver lymphoma · lymphoma of liver · lymphoma of the liver · primary hepatic lymphoma · primary liver lymphoma
Disease family
This is a subtype of liver cancer. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › digestive system disorder › digestive system cancer › liver cancer › liver lymphoma
Related subtypes (4): liver sarcoma, biliary tract cancer, calcifying nested epithelial stromal tumor of the liver, carcinoma of liver and intrahepatic biliary tract
Subtypes (1): liver diffuse large B-cell lymphoma
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 1.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT04115631 | PHASE2 | ACTIVE_NOT_RECRUITING | A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell Lymphoma |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| ACALABRUTINIB | 4 | 1 |
| BENDAMUSTINE | 4 | 1 |
| RITUXIMAB | 4 | 1 |
| CHEMBL4747506 | 0 | 1 |
| CHEMBL5187554 | 0 | 1 |
| CHEMBL5276925 | 0 | 1 |
Related Atlas pages
- Drugs: Acalabrutinib, Bendamustine, Rituximab