Low grade central osteosarcoma

Summary

Low grade central osteosarcoma (MONDO:0006271) is a disease and 1 clinical trial. A subtype of osteosarcoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 1

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	low grade central osteosarcoma
Mondo ID	MONDO:0006271
NCIT	C6474
UMLS	C3814534
MedGen	818980
Is cancer (heuristic)	no

Also known as: intraosseous well-differentiated osteogenic sarcoma · intraosseous well-differentiated osteosarcoma · low grade central osteosarcoma · low grade intramedullary osteosarcoma · low-grade central osteosarcoma · low-grade intramedullary osteosarcoma

Disease family

This is a subtype of osteosarcoma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › cancer › sarcoma › osteosarcoma › low grade central osteosarcoma

Related subtypes (5): localized osteosarcoma, extraosseous osteosarcoma, multifocal osteogenic sarcoma, pediatric osteosarcoma, bone osteosarcoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 1.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT05515068	Not specified	NOT_YET_RECRUITING	Registry For Children, Adolescents And Adults With Osteosarcoma And Biologically Related Bone Sarcomas