Low grade vulvar intraepithelial neoplasia

Summary

Low grade vulvar intraepithelial neoplasia (MONDO:0006274) is a disease and 4 clinical trials. A subtype of vulvar intraepithelial neoplasia — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 4

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	low grade vulvar intraepithelial neoplasia
Mondo ID	MONDO:0006274
EFO	EFO:1000330
NCIT	C4760
UMLS	C0495106
MedGen	99217
GARD	0024357
Is cancer (heuristic)	no

Also known as: grade 1 VIN · grade 1 vulvar intraepithelial neoplasia · grade I VIN · grade I vulvar intraepithelial neoplasia · intraepithelial neoplasia of the vulva grade 1 · intraepithelial neoplasia of vulva grade 1 · low grade VIN · VIN 1 · VIN 1 of usual type · VIN grade 1 · vulva intraepithelial neoplasia grade 1 · vulvar flat condyloma · vulvar intraepithelial neoplasia 1 of usual type · vulvar intraepithelial neoplasia grade 1 · vulvar Low grade squamous intraepithelial lesion · vulvar Low-grade squamous intraepithelial lesion · vulvar mild squamous dysplasia

Disease family

This is a subtype of vulvar intraepithelial neoplasia. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › epithelial neoplasm › squamous cell neoplasm › vulvar squamous neoplasm › vulvar intraepithelial neoplasia › low grade vulvar intraepithelial neoplasia

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 4.

Phase distribution (across all retrieved trials)

Phase	Trials
PHASE3	4

Top trials by phase / activity

NCT	Phase	Status	Title
NCT04422366	PHASE3	RECRUITING	Evaluate the Efficacy, Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females
NCT04895020	PHASE3	RECRUITING	Immunobridging Study of 9-valent Human Papillomavirus Recombinant Vaccine in Chinese Females Aged 9 to 19 Years
NCT04425291	PHASE3	COMPLETED	Evaluate the Immunogenicity and Safety of 4-valent and 9-valent HPV Recombinant Vaccine in Chinese Healthy Females
NCT05372016	PHASE3	COMPLETED	Evaluate the Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females