Lymphocele

Summary

Lymphocele (MONDO:0002968) is a disease and 14 clinical trials. Top therapeutic interventions include lanreotide and fibrin. A subtype of lymphatic system disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 14

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	lymphocele
Mondo ID	MONDO:0002968
MeSH	D008210
DOID	DOID:4347
ICD-11	1806199285
SNOMED CT	234110002
UMLS	C0024248
MedGen	7414
Is cancer (heuristic)	no

Disease family

This is a subtype of lymphatic system disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › immune system disorder › lymphoid system disorder › lymphatic system disorder › lymphocele

Related subtypes (13): lymphatic system cancer, bubonic plague, splenic disorder, histiocytosis, lymph node disorder, lymphangitis, lymphogranuloma venereum, lymphangiectasis, hemophagocytic syndrome, plastic bronchitis, lymphedema, lymphatic vessel neoplasm, pseudolymphoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 14.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	9
PHASE3	3
PHASE4	2

Top trials by phase / activity

NCT	Phase	Status	Title
NCT03752606	PHASE4	COMPLETED	Application of Tachosil During Lymphadenectomy
NCT06258486	PHASE4	UNKNOWN	Ultrasound Guided Inguinal Indocyanine Green Injection to Identify and Pre-emptively Seal Lymphatic Leaks
NCT00630695	PHASE3	COMPLETED	Prevention of Lymphorrhea by Lanreotide in Axillary Dissection for Breast Cancer
NCT01631448	PHASE3	COMPLETED	Fibrin Based Adhesive for the Prevention of Surgical Complications in the Kidney Transplantation
NCT03914963	PHASE3	COMPLETED	Efficacy of a Fibrin Sealant for the Prevention of Lymphocele After Lymphadenectomy
NCT04819542	Not specified	RECRUITING	Use of Compression Bandages in the Prevention of Post-mastectomy Lymphoceles
NCT01644136	Not specified	TERMINATED	Microspheres in Preventing Lymphatic Fluid Collection After Surgery in Patients With Prostate Cancer
NCT01742975	Not specified	COMPLETED	Efficacy Study of Ifabond in Breast Cancer Surgery
NCT02035475	Not specified	COMPLETED	Prevention of Lymphoceles After Robotic PLND
NCT02800980	Not specified	UNKNOWN	Management of Symptomatic Post-operative Lymphocele
NCT03765320	Not specified	COMPLETED	Impact of Peritoneal Closure and Retroperitoneal Drainage on Patients Who Underwent Laparotomic Retroperitoneal Lymph Node Dissection
NCT03791736	Not specified	TERMINATED	Evaluation of Impact of Sandostatin® Injection Before Axillary Clearance on Lymphocele Formation
NCT04205864	Not specified	COMPLETED	Application of Thrombin Gel Matrix for the Prevention of Lymphocele in Patients With Endometrial Cancer.
NCT05398458	Not specified	COMPLETED	Management of a Giant Lymphocele Following Varicose Vein Surgery - A Case Report

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
LANREOTIDE	4	1
FIBRIN	3	1
CHEMBL443232	0	2