Malignant cardiac germ cell tumor

Summary

Malignant cardiac germ cell tumor (MONDO:0001991) is a cancer. A subtype of heart cancer — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	malignant cardiac germ cell tumor
Mondo ID	MONDO:0001991
DOID	DOID:14535
NCIT	C5371
UMLS	C1334566
MedGen	233143
GARD	0023053
Anatomy (UBERON)	UBERON:0000948
Is cancer (heuristic)	yes

Also known as: malignant Cardiac germ cell neoplasm · malignant Cardiac germ cell tumor · malignant germ cell neoplasm of heart · malignant germ cell neoplasm of the heart · malignant germ cell tumor of heart · malignant germ cell tumor of the heart · malignant germ cell tumour of heart · malignant heart germ cell neoplasm · malignant heart germ cell tumor · malignant heart germ cell tumour

Disease family

This is a subtype of heart cancer. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › cancer › cardiovascular cancer › heart cancer › malignant cardiac germ cell tumor

Related subtypes (6): pericardium cancer, heart sarcoma, endocardium cancer, heart lymphoma, myocardium cancer, neurofibroma of the heart

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.