Malignant melanocytic neoplasm of the peripheral nerve sheath
disease diseaseOn this page
Also known as malignant melanocytic neoplasm of peripheral nerve sheathmalignant melanocytic peripheral nerve sheath tumormalignant melanocytic peripheral nerve sheath tumourmalignant melanotic peripheral nerve sheath tumormalignant melanotic peripheral nerve sheath tumourmelanocytic MPNSTmelanotic malignant nerve sheath tumourmelanotic malignant peripheral nerve sheath tumor (morphologic abnormality)melanotic malignant peripheral nerve sheath tumour (morphologic abnormality)
Summary
Malignant melanocytic neoplasm of the peripheral nerve sheath (MONDO:0003863) is a cancer. A subtype of malignant peripheral nerve sheath tumor — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Classification: Cancer
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | malignant melanocytic neoplasm of the peripheral nerve sheath |
| Mondo ID | MONDO:0003863 |
| DOID | DOID:6345 |
| NCIT | C4748 |
| SNOMED CT | 404039004 |
| UMLS | C0474847 |
| MedGen | 99184 |
| GARD | 0023703 |
| Is cancer (heuristic) | yes |
Also known as: malignant melanocytic neoplasm of peripheral nerve sheath · malignant melanocytic neoplasm of the peripheral nerve sheath · malignant melanocytic peripheral nerve sheath tumor · malignant melanocytic peripheral nerve sheath tumour · malignant melanotic peripheral nerve sheath tumor · malignant melanotic peripheral nerve sheath tumour · melanocytic MPNST · melanotic malignant nerve sheath tumour · melanotic malignant peripheral nerve sheath tumor (morphologic abnormality) · melanotic malignant peripheral nerve sheath tumour (morphologic abnormality)
Disease family
This is a subtype of malignant peripheral nerve sheath tumor. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › cancer › nervous system cancer › central nervous system cancer › central nervous system sarcoma › malignant peripheral nerve sheath tumor › malignant melanocytic neoplasm of the peripheral nerve sheath
Related subtypes (6): malignant cardiac peripheral nerve sheath neoplasm, childhood malignant schwannoma, epithelioid malignant peripheral nerve sheath tumor, adult malignant schwannoma, malignant glandular tumor of peripheral nerve sheath, malignant triton tumor
Subtypes (2): melanotic psammomatous malignant peripheral nerve sheath tumor, malignant melanocytic peripheral nerve sheath tumor of mediastinum
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 0.
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.