Malignant teratoma of testis
disease diseaseOn this page
Also known as immature teratoma of testisimmature teratoma of the testisimmature testicular teratomamalignant teratoma of the testismalignant testicular teratomatesticular immature teratomatesticular malignant teratomatestis malignant teratoma
Summary
Malignant teratoma of testis (MONDO:0021282) is a disease and 1 clinical trial. Top therapeutic interventions include palbociclib. A subtype of malignant testicular germ cell tumor — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 1
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | malignant teratoma of testis |
| Mondo ID | MONDO:0021282 |
| ICD-11 | 1214355345 |
| NCIT | C6353 |
| SNOMED CT | 416769008 |
| UMLS | C1334154 |
| MedGen | 232636 |
| GARD | 0025305 |
| Anatomy (UBERON) | UBERON:0000473 |
| Is cancer (heuristic) | no |
Also known as: immature teratoma of testis · immature teratoma of the testis · immature testicular teratoma · malignant teratoma of the testis · malignant testicular teratoma · testicular immature teratoma · testicular malignant teratoma · testis malignant teratoma
Disease family
This is a subtype of malignant testicular germ cell tumor. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › cancer › reproductive system cancer › male reproductive organ cancer › testicular cancer › malignant testicular germ cell tumor › malignant teratoma of testis
Related subtypes (5): mixed testicular germ cell cancer, testicular non-seminomatous germ cell cancer, testicular seminoma, testis refractory cancer, testis polyembryoma
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 1.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT01037790 | PHASE2 | COMPLETED | Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| PALBOCICLIB | 4 | 1 |
Related Atlas pages
- Drugs: Palbociclib