Malignant thyroid stimulating hormone producing neoplasm of pituitary gland

Summary

Malignant thyroid stimulating hormone producing neoplasm of pituitary gland (MONDO:0003836) is a cancer. A subtype of TSH producing pituitary tumor — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	malignant thyroid stimulating hormone producing neoplasm of pituitary gland
Mondo ID	MONDO:0003836
DOID	DOID:6274
NCIT	C5965
UMLS	C1334627
MedGen	277341
GARD	0023688
Is cancer (heuristic)	yes

Also known as: malignant pituitary gland thyrotropinoma · malignant pituitary thyrotropinoma · malignant thyroid stimulating hormone producing neoplasm of pituitary · malignant thyroid stimulating hormone producing neoplasm of pituitary gland · malignant thyroid stimulating hormone producing neoplasm of the pituitary · malignant thyroid stimulating hormone producing neoplasm of the pituitary gland · malignant thyroid stimulating hormone producing pituitary gland neoplasm · malignant thyroid stimulating hormone producing pituitary gland tumor · malignant thyroid stimulating hormone producing pituitary gland tumour · malignant thyroid stimulating hormone producing pituitary neoplasm · malignant thyroid stimulating hormone producing pituitary tumor · malignant thyroid stimulating hormone producing pituitary tumour · malignant thyroid stimulating hormone producing tumor · malignant thyroid stimulating hormone producing tumor of pituitary · malignant thyroid stimulating hormone producing tumor of pituitary gland · malignant thyroid stimulating hormone producing tumor of the pituitary · malignant thyroid stimulating hormone producing tumor of the pituitary gland · malignant thyroid stimulating hormone producing tumour · malignant thyroid stimulating hormone producing tumour of pituitary · malignant thyroid stimulating hormone producing tumour of pituitary gland (+64 more)

Disease family

This is a subtype of TSH producing pituitary tumor. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › endocrine gland neoplasm › pituitary tumor › functioning pituitary gland neoplasm › functioning pituitary gland adenoma › TSH producing pituitary tumor › malignant thyroid stimulating hormone producing neoplasm of pituitary gland

Related subtypes (1): TSH-secreting pituitary adenoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.