Malignant tumor of meninges
diseaseOn this page
Also known as cancer of meningeal clustercancer of meningescancer of the meningesmalignant meningeal cluster neoplasmmalignant meningeal neoplasmsmalignant meningeal tumormalignant meningeal tumourmalignant meninges neoplasmmalignant meninges tumormalignant meninges tumourmalignant neoplasm of meningeal clustermalignant neoplasm of meningesmalignant neoplasm of the meningesmalignant neoplasms of meningesmalignant tumor of the meningesmalignant tumour of the meningesmeningeal cancermeningeal cluster cancermeningeal tumors, malignant
Summary
Malignant tumor of meninges (MONDO:0021322) is a cancer (an umbrella term covering 10 Mondo subtypes) and 1 clinical trial. Top therapeutic interventions include mafosfamide. A subtype of central nervous system cancer — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Classification: Cancer
- Umbrella term: 10 Mondo subtypes
- Clinical trials: 1
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | malignant tumor of meninges |
| Mondo ID | MONDO:0021322 |
| ICD-10-CM | C70 |
| NCIT | C4628 |
| SNOMED CT | 363497007 |
| UMLS | C0348375 |
| MedGen | 87594 |
| GARD | 0025313 |
| Anatomy (UBERON) | UBERON:0010743 |
| Is cancer (heuristic) | yes |
Also known as: cancer of meningeal cluster · cancer of meninges · cancer of the meninges · malignant meningeal cluster neoplasm · malignant meningeal neoplasms · malignant meningeal tumor · malignant meningeal tumour · malignant meninges neoplasm · malignant meninges tumor · malignant meninges tumour · malignant neoplasm of meningeal cluster · malignant neoplasm of meninges · malignant neoplasm of the meninges · malignant neoplasms of meninges · malignant tumor of the meninges · malignant tumour of the meninges · meningeal cancer · meningeal cluster cancer · meningeal tumors, malignant
Disease family
This is a subtype of central nervous system cancer. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › cancer › nervous system cancer › central nervous system cancer › malignant tumor of meninges
Related subtypes (19): central nervous system primitive neuroectodermal neoplasm, brain cancer, central nervous system sarcoma, primary central nervous system lymphoma, central nervous system germinoma, central nervous system melanocytic neoplasm, central nervous system endodermal sinus tumor, spinal cord cancer, malignant carotid body paraganglioma, malignant adrenal gland pheochromocytoma, malignant jugulotympanic paraganglioma, pheochromocytoma/paraganglioma syndrome 2, pheochromocytoma/paraganglioma syndrome 5, central nervous system Ewing sarcoma/peripheral primitive neuroectodermal tumor, choriocarcinoma of the central nervous system, mixed germ cell tumor of central nervous system, embryonal carcinoma of the central nervous system, malignant central nervous system mesenchymal, non-meningothelial neoplasm, malignant glioma
Subtypes (10): intraventricular meningioma, meninges hemangiopericytoma, lung meningioma, malignant leptomeningeal tumor, cerebral meningioma, spinal meninges cancer, meningeal sarcoma, skin meningioma, meningeal melanomatosis, anaplastic meningioma
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 1.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| PHASE1 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT00062881 | PHASE1 | COMPLETED | Intrathecal Mafosfamide |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| MAFOSFAMIDE | 2 | 1 |
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.