Mediastinal yolk sac tumor
diseaseOn this page
Also known as endodermal sinus neoplasm of mediastinumendodermal sinus neoplasm of the mediastinumendodermal sinus tumor of mediastinumendodermal sinus tumor of the mediastinumendodermal sinus tumour of mediastinumendodermal sinus tumour of the mediastinumESTmediastinal endodermal sinus neoplasmmediastinal endodermal sinus tumormediastinal endodermal sinus tumorsmediastinal endodermal sinus tumourmediastinal endodermal sinus tumoursmediastinal yolk Sac neoplasmmediastinal yolk Sac tumourmediastinum yolk sac tumormediastinum yolk sac tumouryolk Sac neoplasm of mediastinumyolk Sac neoplasm of the mediastinumyolk Sac tumor of mediastinum
Summary
Mediastinal yolk sac tumor (MONDO:0023726) is a cancer. A subtype of yolk sac tumor — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Classification: Cancer
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | mediastinal yolk sac tumor |
| Mondo ID | MONDO:0023726 |
| NCIT | C6443 |
| UMLS | C1334683 |
| MedGen | 233176 |
| GARD | 0008258 |
| Anatomy (UBERON) | UBERON:0003728 |
| Is cancer (heuristic) | yes |
Also known as: endodermal sinus neoplasm of mediastinum · endodermal sinus neoplasm of the mediastinum · endodermal sinus tumor of mediastinum · endodermal sinus tumor of the mediastinum · endodermal sinus tumour of mediastinum · endodermal sinus tumour of the mediastinum · EST · mediastinal endodermal sinus neoplasm · mediastinal endodermal sinus tumor · mediastinal endodermal sinus tumors · mediastinal endodermal sinus tumour · mediastinal endodermal sinus tumours · mediastinal yolk Sac neoplasm · mediastinal yolk Sac tumor · mediastinal yolk Sac tumour · mediastinum yolk sac tumor · mediastinum yolk sac tumour · yolk Sac neoplasm of mediastinum · yolk Sac neoplasm of the mediastinum · yolk Sac tumor of mediastinum (+3 more)
Disease family
This is a subtype of yolk sac tumor. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › cancer › malignant germ cell tumor › extragonadal germ cell cancer › extragonadal nonseminomatous germ cell tumor › yolk sac tumor › mediastinal yolk sac tumor
Related subtypes (6): vaginal yolk sac tumor, childhood endodermal sinus tumor, testicular yolk sac tumor, adult yolk sac tumor, ovarian yolk sac tumor, yolk sac tumor of central nervous system
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 0.
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.