Melanotic neuroectodermal tumor

Summary

Melanotic neuroectodermal tumor (MONDO:0002072) is a cancer. A subtype of primitive neuroectodermal tumor — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	melanotic neuroectodermal tumor
Mondo ID	MONDO:0002072
MeSH	D017600
DOID	DOID:166
NCIT	C3717
SNOMED CT	404042005
UMLS	C0206094
MedGen	60073
Is cancer (heuristic)	yes

Also known as: infantile melanotic neuroectodermal neoplasm · melanotic neuroectodermal tumor (morphologic abnormality) · melanotic neuroectodermal tumor of infancy · melanotic neuroectodermal tumor of infancy (morphologic abnormality) · melanotic neuroectodermal tumour (morphologic abnormality) · melanotic neuroectodermal tumour of infancy (morphologic abnormality) · melanotic Progonoma · MNTI · pigmented neuroectodermal tumor · pigmented neuroectodermal tumor of infancy · pigmented neuroectodermal tumour · retinal anlage neoplasm

Data availability: 4 cell lines.

Disease family

This is a subtype of primitive neuroectodermal tumor. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › embryonal neoplasm › primitive neuroectodermal tumor › melanotic neuroectodermal tumor

Related subtypes (4): central nervous system primitive neuroectodermal neoplasm, neuroblastic tumor, primitive neuroectodermal tumor of the corpus uteri, peripheral primitive neuroectodermal tumor

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.