Meralgia paresthetica

Summary

Meralgia paresthetica (MONDO:0023757) is a disease and 13 clinical trials. A subtype of nerve compression syndrome — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 13

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	meralgia paresthetica
Mondo ID	MONDO:0023757
MeSH	C537458
ICD-10-CM	G57.1
SNOMED CT	85007004
UMLS	C0152110
MedGen	101817
GARD	0009417
Is cancer (heuristic)	no

Also known as: Bernhardt-Roth syndrome · lateral femoral cutaneous nerve entrapment · meralgia paraesthetica familial (type)

Disease family

This is a subtype of nerve compression syndrome. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › nervous system disorder › peripheral nervous system disorder › peripheral neuropathy › nerve compression syndrome › meralgia paresthetica

Related subtypes (2): carpal tunnel syndrome, piriformis syndrome

Subtypes (1): meralgia paraesthetica, familial

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 13.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	12
PHASE3	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT02577510	PHASE3	COMPLETED	Comparing Ways to Freeze the Nerve That Provides Thigh Sensation
NCT07328360	Not specified	RECRUITING	The Efficacy of High-Power Laser Therapy in Meralgia Paresthetica
NCT07335822	Not specified	RECRUITING	The Effectiveness of Low-Level Laser Therapy in the Treatment of Meralgia Paresthetica
NCT04004052	Not specified	COMPLETED	Conservative Treatment and Ultrasound Guided Injection for Treatment Meralgia Paresthetica
NCT04046406	Not specified	WITHDRAWN	Pelvic Pain Treated With MR-guided Cryoanalgesia
NCT04499911	Not specified	COMPLETED	Efficacy of Neural Prolotherapy in Treatment of Meralgia Paresthetica
NCT04747119	Not specified	COMPLETED	Effect of MET on Meralgia Paraesthesia Postpartum Muscle Energy Technique
NCT05893732	Not specified	COMPLETED	HILT for Meralgia Paresthetica
NCT06187883	Not specified	COMPLETED	Pulsed Radiofrequency of Lateral Femoral Cutaneous Nerve
NCT06251882	Not specified	COMPLETED	Efficacy of Ultrasound-guided Injection of 5% Dextrose for Meralgia Paresthesia
NCT06683924	Not specified	COMPLETED	Pulsed Radiofrequency Ablation and Steroid Injections for the Treatment of Meralgia Paresthetica
NCT06751147	Not specified	COMPLETED	Effects of Lateral Femoral Cutaneous Nerve Mobilization With and Without Muscle Energy Techniques in Pregnant Females
NCT07089472	Not specified	COMPLETED	Dry Needling Versus Cyriax Technique on Pain, Paraesthesia and Functional Disability in Patients With Chronic Low Back Pain