Middle cerebral artery infarction

Summary

Middle cerebral artery infarction (MONDO:0006857) is a disease and 5 clinical trials. A subtype of cerebral infarction — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 5

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	middle cerebral artery infarction
Mondo ID	MONDO:0006857
EFO	EFO:1001045
MeSH	D020244
DOID	DOID:3525
UMLS	C0740392
MedGen	152845
Is cancer (heuristic)	no

Disease family

This is a subtype of cerebral infarction. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › nervous system disorder › central nervous system disorder › brain disorder › cerebrovascular disorder › brain infarction › cerebral infarction › middle cerebral artery infarction

Related subtypes (3): anterior cerebral artery infarction, posterior cerebral artery infarction, multi-infarct dementia

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 5.

Phase distribution (across all retrieved trials)

Phase	Trials
PHASE2	3
EARLY_PHASE1	1
Not specified	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT00950521	PHASE2	COMPLETED	Efficacy Study of CD34 Stem Cell in Chronic Stroke Patients
NCT01461720	PHASE2	UNKNOWN	Intravenous Autologous Mesenchymal Stem Cells Transplantation to Treat Middle Cerebral Artery Infarct
NCT02425670	PHASE2	COMPLETED	Stem Cell Therapy For Acute Ischemic Stroke Patients
NCT00612300	EARLY_PHASE1	COMPLETED	Gait Training for Persons With Stroke
NCT02609256	Not specified	TERMINATED	Stereotactic Infarct Tissue Aspiration for Malignant Infarction of Middle Cerebral Artery