Mild pre-eclampsia

Summary

Mild pre-eclampsia (MONDO:0001072) is a disease and 4 clinical trials. Top therapeutic interventions include methyldopa and methyldopa (racemic). A subtype of preeclampsia — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 4

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	mild pre-eclampsia
Mondo ID	MONDO:0001072
DOID	DOID:10590
ICD-11	690705840
SNOMED CT	41114007
UMLS	C0269658
MedGen	542203
Is cancer (heuristic)	no

Disease family

This is a subtype of preeclampsia. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › disease of genetic or genomic mechanism › hereditary disease › preeclampsia › mild pre-eclampsia

Related subtypes (6): severe pre-eclampsia, preeclampsia/eclampsia 2, preeclampsia/eclampsia 3, preeclampsia/eclampsia 4, preeclampsia/eclampsia 5, preeclampsia/eclampsia 1

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 4.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	4

Top trials by phase / activity

NCT	Phase	Status	Title
NCT01906567	Not specified	UNKNOWN	İs There a Relationship Between Severity of Preeclampsia and Maternal Heavy Metal Levels?
NCT02164370	Not specified	COMPLETED	Evaluation of Metabolic Acid-base Abnormalities in Pre-eclamptic Women Applying the Stewart-Fencl Approach
NCT05888896	Not specified	UNKNOWN	Effect of Foot Reflexology on Preeclampsia
NCT06907576	Not specified	COMPLETED	Labor Characteristics and Outcomes in Women With Gestational Hypertension or Preeclampsia Who Underwent Labor Induction

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
METHYLDOPA	4	1
METHYLDOPA (RACEMIC)	1	1